204125-01-9

Basic information

• Product Name: C₄₅H₄₈Cl₅NO₁₄
• Synonyms: C₄₅H₄₈Cl₅NO₁₄
• CAS NO: 204125-01-9
• Molecular Weight: 1004.14
• Mol File: 204125-01-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₅H₄₈Cl₅NO₁₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₅H₄₈Cl₅NO₁₄(204125-01-9)
• EPA Substance Registry System: C₄₅H₄₈Cl₅NO₁₄(204125-01-9)

Safety Data

• Hazardous Substances Data: 204125-01-9(Hazardous Substances Data)

Upstream product

• 204124-97-0 7-trichloroacetylbaccatin III 

Downstream Products

• 261728-77-2 7-trichloroacetyl-3'-debenzoylpaclitaxel 
• 502626-35-9 C₅₁H₆₂Cl₃NO₁₅ 
• 502626-31-5 C₅₀H₅₈Cl₃NO₁₅ 
• 502626-32-6 C₅₀H₆₀Cl₃NO₁₅ 
• 502626-33-7 C₅₀H₅₈Cl₃NO₁₅ 
• 502626-34-8 C₅₁H₅₀Cl₃NO₁₅ 
• 502626-29-1 C₄₉H₅₈Cl₃NO₁₅ 
• 502626-30-4 C₅₀H₅₆Cl₃NO₁₅ 
• 502626-26-8 C₄₈H₅₄Cl₃NO₁₅ 
• 502626-23-5 C₄₇H₅₂Cl₃NO₁₅ 
• 502626-21-3 C₄₇H₅₂Cl₃NO₁₅ 
• 502626-17-7 C₄₆H₅₀Cl₃NO₁₅ 
• 502626-19-9 C₄₆H₅₀Cl₃NO₁₅ 
• 502626-20-2 C₄₆H₄₈Cl₃NO₁₅ 

Relevant articles and documents

Synthesis and biology of 3'-N-acyl-N-debenzoylpaclitaxel analogues

The 3'-N-acyl-N-debenzoylpaclitaxel analogues 1a-d were synthesized and evaluated on biological systems. Some of the analogues 1a-d exhibited higher cytotoxicities (up to 20-fold) and stronger abilities to induce apoptosis than paclitaxel. In an in vivo experiment against ip implanted B16 melanoma, the most cytotoxic compound 1b in vitro caused tumor growth inhibition more than paclitaxel.