204129-67-9Relevant articles and documents
Design, synthesis, and biological evaluation of potent thiazine- and thiazepine-based matrix metalloproteinase inhibitors
Almstead, Neil G.,Bradley, Rimma S.,Pikul, Stanislaw,De, Biswanath,Natchus, Michael G.,Taiwo, Yetunde O.,Gu, Fei,Williams, Lisa E.,Hynd, Barbara A.,Janusz, Michael J.,Dunaway, C. Michelle,Mieling, Glen E.
, p. 4547 - 4562 (2007/10/03)
The synthesis and enzyme inhibition data for a series of thiazine- and thiazepine-based matrix metalloproteinase (MMP) inhibitors are described. The thiazine- and thiazepine-based inhibitors were discovered by optimization of hetererocyclic sulfonamide-ba