204137-96-2

Upstream product

• 1051966-19-8 N-tert-butyloxycarbonyl-L-prolinol-p-tosylate 
• 825-83-2 4-trifluoromethylbenzenethiol 
• 128542-75-6 (S)-2-(bromomethyl)-1-<(tert-butyloxy)carbonyl>pyrrolidine 

Downstream Products

• 314019-57-3 (S)-tert-butyl 2-{[4-(trifluoromethyl)phenyl]sulfinylmethyl}-pyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

11β LONG-CHAIN SUBSTITUTED ESTRATRIENES, METHOD FOR THEIR PRODUCTION, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11β LONG-CHAIN SUBSTITUTED ESTATRIENES, AND THEIR USE FOR PRODUCING MEDICAMENTS

This invention describes a 11β-long-chain-substituted estratriene of general formula (I), in which R11is a long-chain radical that has a nitrogen atom and optionally a sulfur atom, which in addition can be functionalized in the terminal positio

7α-(ξ-aminoalkyl)-estratrienes, process for their production, pharmaceutical preparations which contain these 7α-(ξ-aminoalkyl)-estratrienes as well as their use for the production of pharmaceutical agents

This invention describes new, substituted 7α-(ξ-aminoalkyl)-estratrienes of general formula I STR1 in which side chain SK is a radical of partial formula STR2 as well as their physiologically compatible addition salts with organic and inorganic acids. The new compounds represent compounds with very strong antiestrogenic action. The compounds according to the invention are, on the one hand, pure antiestrogens, or, on the other hand, antiestrogens with estrogenic partial action. Based on this spectrum of action, the new compounds are highly suitable for the production of pharmaceutical agents for tumor therapy and hormone replacement treatment.