20416-08-4Relevant articles and documents
Synthesis of substituted 3-furanoates from MBH-acetates of acetylenic aldehydes via tandem isomerization-deacetylation-cycloisomerization: Access to Elliott's alcohol
Reddy, Chada Raji,Krishna, Gaddam,Reddy, Motatipally Damoder
, p. 1664 - 1670 (2014/03/21)
A new method for the synthesis of 5-substituted furan-3-carboxylates from Morita-Baylis-Hillman acetates of acetylenic aldehydes is reported. The process involves palladium-catalyzed isomerization followed by base-promoted deacetylation and cycloisomerization reactions. The utility of this chemistry is further demonstrated by the synthesis of Elliott's alcohol, a key intermediate of the pyrethroid resmethrins. This journal is The Royal Society of Chemistry 2014.