204259-94-9Relevant academic research and scientific papers
A paclitaxel analogue with a 2(3→20)abeotaxane skeleton: Synthesis and biological evaluation
Soto, Javier,Mascarenas, Jose L.,Castedo, Luis
, p. 273 - 276 (1998)
A paclitaxel analogue having an unusual tricyclic [9.3.1.1] hexadecane skeleton was synthesized from deaminoacyltaxine A, a 2(3→20) abeotaxane isolated in considerable amounts from the leaves of Taxus baccata L. In preliminary studies, this compound showed a much lower cytotoxicity than paclitaxel.
