204274-94-2Relevant academic research and scientific papers
Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases
Pikul, Stanislaw,McDow Dunham, Kelly L.,Almstead, Neil G.,De, Biswanath,Natchus, Michael G.,Anastasio, Melanie V.,McPhail, Sara J.,Snider, Catherine E.,Taiwo, Yetunde O.,Chen, Longyin,Dunaway, C. Michelle,Gu, Fei,Mieling, Glen E.
, p. 87 - 94 (2007/10/03)
A new series of hydroxamic acid-based matrix metalloproteinase (MMP) inhibitors containing a unique phosphinamide motif derived from D-amino acid was designed, synthesized, and tested for enzyme inhibition. Compounds with an R configuration at phosphorus
