204334-80-5

Upstream product

• 1119-67-1 1-iodo-1-hexyne 
• 148651-37-0 (2-bromophenyl)zinc(II)iodide 
• 583-55-1 1-Bromo-2-iodobenzene 
• 79887-10-8 1-ethynyl-4-(n-pentyl)benzene 
• 542-69-8 1-iodo-butane 
• 766-46-1 2-bromo-1-ethynylbenzene 
• 1009364-05-9 1-bromo-2-(1,1-dibromohex-1-en-2-yl)benzene 
• 693-02-7 hex-1-yne 

Downstream Products

• 1192159-92-4 benzyl 2-butyl-1H-indole-1-carboxylate 
• 889766-05-6 (2-(hex-1-yn-1-yl)phenyl)boronic acid 
• 1324008-41-4 [2-(hex-1-ynyl)phenyl]dimethyl(2-methylprop-1-enyl)silane 
• 1415462-03-1 2-(2-(hex-1-yn-1-yl)phenyl)benzofuran 
• 1614230-99-7 1-bromo-2-((1E,3Z)-hexa-1,3-dienyl)benzene 
• 1614230-98-6 1-bromo-2-((1E,3E)-hexa-1,3-dienyl)benzene 
• 1361452-34-7 11-allyl-6-butyl-11-phenyl-11H-indeno[1,2-c]quinoline 
• 1338797-95-7 7-butyl-12-phenylbenzo[c]indeno[2,1-e]azepin-5(6H)-one 
• 1338798-07-4 ethyl 4-(7-butyl-5-oxo-12-phenylbenzo[c]indeno[2,1-e]azepin-6(5H)-yl)benzoate 
• 1329007-40-0 6-butyl-11-(p-tolyl)-11H-indeno[1,2-c]quinolin-11-ol 
• 1329007-38-6 6-butyl-11-phenyl-11H-indeno[1,2-c]quinolin-11-ol 
• 1329007-42-2 6-butyl-2-methyl-11-(p-tolyl)-11H-indeno[1,2-c]quinolin-11-ol 

Relevant academic research and scientific papers

Metal-Free Aminoiodination of Alkynes Under Visible Light Irradiation for the Construction of a Nitrogen-Containing Eight-Membered Ring System

A method for the synthesis of dihydrodibenzo[c,e]azocine derivatives via a regioselective intramolecular aminoiodination of alkynes under visible light irradiation has been developed. This protocol uses a combination of iodine and hypervalent iodine to re

Trithiocarbonate Anion as a Sulfur Source for the Synthesis of 2,5-Disubstituted Thiophenes and 2-Substituted Benzo[ b]thiophenes

The trithiocarbonate anion (CS32-) was generated in situ from CS2 and KOH in dimethyl sulfoxide by a simple method and used as a novel synthetic equivalent of the S2- synthon for the synthesis of 2,5-disubstituted thiophenes from 1,3-butadiynes. Additionally, this system was employed for the metal-free synthesis of 2-substituted benzo[b]thiophenes from 2-haloalkynyl (hetero)arenes. These compounds were obtained from a cheap and readily available sulfur source in moderate to good yields, with good functional group tolerance.

Synthesis of Cycloheptatrienes, Oxepines, Thiepines, and Silepines: A Comparison between Br?nsted Acid and Au-Catalysis

The cyclization of 1-(benzyl-, oxyaryl-, thioaryl-, and silaaryl)-2-ethynylbenzenes under Br?nsted acid- and Au(I)-catalysis is described. Br?nsted acid catalysis favors without exception the formation of the products derived from the regioselective proto

Selective Synthesis of Phenanthrenes and Dihydrophenanthrenes via Gold-Catalyzed Cycloisomerization of Biphenyl Embedded Trienynes

Readily available o′-alkenyl-o-alkynylbiaryls, a particular type of 1,7-enynes, undergo a selective cycloisomerization reaction in the presence of a gold(I) catalyst to give interesting phenanthrene and dihydrophenanthrene derivatives in high yields. The solvent used provokes a switch in the evolution of the gold intermediate and plays a key role in the reaction outcome.

Synthesis of Naphthalenyl Triflates via the Cationic Annulation of Benzodiynes with Triflic Acid

A highly efficient and regioselective annulation of benzodiynes promoted by triflic acid has been developed. This protocol provides a step and atom-economic access to a series of naphthalenyl triflates. Furthermore, direct synthetic applications of this r

A new class of N-doped ionic PAHs: Via intramolecular [4+2]-cycloaddition between arylpyridines and alkynes

Reported herein, for the first time, is a copper-promoted intramolecular [4+2]-cycloaddition cascade to access ionic N-doped polycyclic aromatic hydrocarbons (PAHs) with tunable emission wavelengths. It is shown that the reaction can be made catalytic with respect to Cu(OTf)2 when an external oxidant, Selectfluor, was used.

Construction of Six-Membered Silacyclic Skeletons via Platinum-Catalyzed Tandem Hydrosilylation/Cyclization with Dihydrosilanes

Catalytic silicon-carbon or silicon-heteroatom bond-forming hydrosilylation has become increasingly important in synthetic chemistry, catalysis and organosilicon chemistry. Herein we report a platinum-catalyzed one-pot and tandem hydrosilylation/cyclization of OH-containing alkynes with dihydrosilanes, allowing for facile synthesis of six-membered organosilicon compounds, including silyloxycycles and cyclic siloxanes in high yields and with good stereoselectivities. (Figure presented.).

Versatile synthesis of Phospholides from open-chain precursors. application to annelated pyrrole- and silole-phosphole rings

Phospholides are easily obtained by treatment of the open-chain acetylenic phosphines shown by an excess of lithium at room temperature in THF (12 examples).

Soft propargylic deprotonation: Designed ligand enables au-catalyzed isomerization of alkynes to 1,3-Dienes

By functionalizing the privileged biphenyl-2-ylphosphine with a basic amino group at the rarely explored 3′ position, the derived gold(I) complex possesses orthogonally positioned "push" and "pull" forces, which enable for the first time soft propargylic deprotonation and permit the bridging of a difference of >26 pKa units (in DMSO) between a propargylic hydrogen and a protonated tertiary aniline. The application of this design led to efficient isomerization of alkynes into versatile 1,3-dienes with synthetically useful scope under mild reaction conditions.

Silver-catalyzed incorporation of carbon dioxide into o-alkynylaniline derivatives

Benzoxazine-2-one derivatives are important heterocycle structures because of their various pharmaceutical activities, though their synthetic methods had been limited. In some cases, toxic reagents, such as phosgene or carbon monoxide, are required. It was found that a silver catalyst successfully promoted the incorporation of CO2 into o-alkynylanilines to afford the corresponding benzoxazine-2-ones bearing Z exo-olefin via 6-exo-dig cyclization at the activated C-C triple bond.