766-46-1

Basic information

• Product Name: 1-BROMO-2-ETHYNYLBENZENE
• Synonyms: 1-BROMO-2-ETHYNYLBENZENE;2'-BROMOPHENYL ACETYLENE;2-BROMOPHENYLACETYLENE;Benzene, 1-broMo-2-ethynyl-;2-Bromophenylacetylene 97%;1-BroMo-2-ethynylbenzene 95%;o-Bromophenylacetylene
• CAS NO: 766-46-1
• Molecular Formula: C₈H₅Br
• Molecular Weight: 181.03
• Product Categories: Aromatic Halides (substituted);Aromatics Compounds;Aromatics;Alkynyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 766-46-1.mol
• Article Data: 44

Chemical Properties

• Boiling Point: 92-93 °C20 mm Hg(lit.)
• Flash Point: 147 °F
• Appearance: Colourless Oil
• Density: 1.443 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.231mmHg at 25°C
• Refractive Index: n20/D 1.595(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Acetone, Dichloromethane, Ethyl Acetate, Hexane
• Stability: Light and Temperature Sensitive.
• CAS DataBase Reference: 1-BROMO-2-ETHYNYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-ETHYNYLBENZENE(766-46-1)
• EPA Substance Registry System: 1-BROMO-2-ETHYNYLBENZENE(766-46-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 766-46-1(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

Different sources of media describe the Uses of 766-46-1 differently. You can refer to the following data:
1. 1-Bromo-2-ethynylbenzene may be used in the synthesis of 1-(2-bromophenyl)-2-(dibenzo[b,d]thiophen-4-yl)ethanone.
2. Starting material for heterocyclotriynes, second-order nonlinear optical materials, and unsymmetrical 1,4-diarylbutadiynes

Synthesis Reference(s)

Tetrahedron Letters, 22, p. 2495, 1981 DOI: 10.1016/S0040-4039(01)92942-9

General Description

1-Bromo-2-ethynylbenzene (BEB) is a haloalkyne. It undergoes Sonogashira coupling with methyl 2-iodobenzoate to form bromo tolane derivative.

InChI:InChI=1/C8H5Br/c1-2-7-5-3-4-6-8(7)9/h1,3-6H

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 38274-16-7 2-bromo-1-(trimethylsilylethynyl)benzene 
• 7345-79-1 2-bromocinnamic acid 
• 583-53-9 2,3-dibromobenzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 74-86-2 acetylene 
• 994-89-8 tributylethynyltin 
• 10448-07-4 2-bromobenzenediazonium tetrafluoroborate 
• 6630-33-7 ortho-bromobenzaldehyde 
• 153140-75-1 1-bromo-2-[(Z)-2-bromoethenyl]benzene 
• 213599-19-0 1-bromo-2-(2,2-dibromovinyl)benzene 
• 18982-54-2 o-bromobenzyl alcohol 
• 64-17-5 ethanol 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 38274-16-7 2-bromo-1-(trimethylsilylethynyl)benzene 
• 38399-13-2 2,2'-dibromotolane 
• 292868-55-4 1-(2-bromophenyl)-2-(3-bromophenyl)ethyne 
• 292868-54-3 1-(2-bromophenyl)-2-(4-iodophenyl)ethyne 
• 383191-52-4 1-(2-Bromo-phenylethynyl)-3,5-dimethyl-benzene 
• 864517-23-7 (E)-(2-bromostyryl)boronic acid 
• 1025731-79-6 N-benzyl-N-methyl-[3-(2-bromophenyl)-2-propynyl]amine 
• 1062590-72-0 C₁₃H₁₀BrF₃O₃ 
• 52889-62-0 2-ethynyl-1,1'-biphenyl 
• 1034024-52-6 2-((2-bromophenyl)ethynyl)thiophene 
• 1109280-57-0 1-(2-bromophenyl)-3,3-diphenylpropan-1-one 
• 1114547-92-0 (Z)-N-(3-(2-bromophenyl)prop-2-ynylidene)cyclohexanamine 
• 1132983-21-1 4-(2-bromophenyl)-1-(4-nitrophenyl)-1H-1,2,3-triazole 
• 1132983-07-3 4-(2-bromophenyl)-1-(2-nitrophenyl)-1H-1,2,3-triazole 

Relevant articles and documents

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