204378-34-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-6-Methoxy-pyridine-2-carboxylic acid is used as an intermediate in the synthesis of pharmaceuticals for its potential biological activities. It plays a crucial role in the development of new drugs, contributing to the advancement of medicine and healthcare.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chloro-6-Methoxy-pyridine-2-carboxylic acid is employed as an intermediate in the synthesis of agrochemicals. Its involvement in the production of these chemicals helps to improve agricultural yields and protect crops from pests and diseases.
Used in Organic Synthesis:
4-Chloro-6-Methoxy-pyridine-2-carboxylic acid is used as a building block in the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable component in the creation of a wide range of organic molecules for diverse applications.

Upstream product

• 1443759-42-9 4-amino-6-methoxy-pyridine-2-carboxylic acid methyl ester 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 1008304-85-5 2-chloro-6-methoxy-pyridin-4-ylamine 
• 204378-37-0 4-chloro-6-methoxy-pyridine-2-carboxylic acid methyl ester 

Downstream Products

• 204378-23-4 N-[(2,6-Dichlorophenyl)sulfonyl]-4-chloro-6-methoxy-2-pyridinecarboxamide 
• 1443757-45-6 [4-(4-chloro-6-methoxy-pyridine-2-carbonyl)-2,2-dimethyl-piperazin-1-yl]-[2-(3-fluoro-phenyl)-2H-tetrazol-5-yl]-methanone 
• 1261726-57-1 C₇H₅Cl₂NO₂ 

Relevant academic research and scientific papers

PIPERAZINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLU5 RECEPTORS

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide

A herbicide containing as the active ingredient an N-(henylsulfonyl)picolinamide derivative represented by general formula (I) wherein X reprcsents a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, a C1-4 haloalkoxy, a (C1-4 alkoxy)carbonyl, a [di(C1-4 alkyl)amino]sulfonyl, an [N—(C1-4 alkyl)-N—(C1-4 alkoxy)amino]sulfonyl, a (C1-4 alkylamino)sulfonyl, a C1-4 alkylthio, a C1-4 alkylsulfinyl, a C1-4 alkylsulfonyl, or nitro; n is an integer of 0 to 5; Y represets a halogeno, a C1-4 alkyl, a C1-4 haloalkyl, a C1-4 alkoxy, C1-4 haloalkoxy, a C1-4 alkylthio, a C1-4 haloalkylthio, amino, a C1-4 alkylamino, a di(C1-4 alkyl)amino, a (C1-4 alkoxy) C1-4 alkyl, a (C1-4 alkylthio) C1-4 alkyl, or nitro; and m is an integer of 0 to 4. This active ingredient is synthesized by condensing a substituted picolinic acid with a substituted benzenesulfonamide under dehydration, or by reacting the phenyl ester of a substituted picolinic acid with a substituted benzenesulfonamide in the presence of a basic compound.