1008304-85-5

Usage

Uses

Used in Organic Synthesis:
2-chloro-6-methoxypyridin-4-amine is used as a building block in organic synthesis for the creation of complex organic molecules with a wide range of applications. Its versatile functional groups allow for various chemical reactions, facilitating the synthesis of novel compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-chloro-6-methoxypyridin-4-amine is utilized as a key intermediate in the development of new drugs. Its structural features make it a candidate for the design of pharmaceutical agents with potential therapeutic effects.
Used in Agriculture:
2-chloro-6-methoxypyridin-4-amine may find applications in the agricultural sector, potentially serving as a component in the development of agrochemicals, such as pesticides or herbicides, due to its chemical reactivity and stability.
Used in Materials Science:
2-chloro-6-methoxypyridin-4-amine is also considered for use in materials science, where it could contribute to the development of new materials with specific properties, such as conductivity or stability, based on its chemical composition and structure.
Further research is essential to fully explore the potential uses and properties of 2-chloro-6-methoxypyridin-4-amine, ensuring its safe and effective application across different industries.

Upstream product

• 67-56-1 methanol 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 124-41-4 sodium methylate 

Downstream Products

• 204378-34-7 4-chloro-6-methoxy-pyridine-2-carboxylic acid 
• 204378-37-0 4-chloro-6-methoxy-pyridine-2-carboxylic acid methyl ester 
• 1060810-46-9 4-bromo-6-methoxy-pyridine-2-carboxylic acid 
• 1256789-39-5 4-bromo-6-methoxy-pyridine-2-carboxylic acid methyl ester 
• 1443757-45-6 [4-(4-chloro-6-methoxy-pyridine-2-carbonyl)-2,2-dimethyl-piperazin-1-yl]-[2-(3-fluoro-phenyl)-2H-tetrazol-5-yl]-methanone 
• 1443759-42-9 4-amino-6-methoxy-pyridine-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis method of 4-bromo-2-chloro-6-methoxypyridine

The invention relates to the technical field of chemical synthesis, and concretely discloses a synthesis method of 4-bromo-2-chloro-6-methoxypyridine, according to the method, 4-bromo-2-chloro-6-methoxypyridine is used as a starting raw material, under the action of a catalyst, through methoxy substitution, and a 4-amino-2-chloro-6-methoxypyridine key intermediate with high yield is obtained, andthen diazotization bromination is carried out to obtain the target product 4-bromo-2-chloro-6-methoxypyridine. The 4-bromine-2-chloro-6-methoxypyridine is an important intermediate for drug synthesis,but the synthetic route of 4-bromine-2-chloro-6-methoxypyridine, especially the synthetic route suitable for commercial mass production, is not reported. The synthetic route of the compound is provided for the first time, the method is particularly suitable for commercial mass production, and the 4-bromine-2-chloro-6-methoxypyridine is prepared with high yield and high purity.

BACE-2 INHIBITORY COMPOUNDS AND RELATED METHODS OF USE

Provided herein are novel compounds of Formulae I-III, and methods of using the same to selectively inhibit BACE2.

PIPERAZINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLU5 RECEPTORS

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS

Provided herein are compounds of formula I: wherein A, B, X, R1 , R2 and subscript n are as defined in the following disclosure. Compositions comprising the compounds are also provided, as well as methods for their use, for example, in treatment of type 2 diabetes and type 2 diabetes-related conditions