204444-44-0 Usage
Chemical class
Corticosteroids
Derivative of
Prednisolone
Structural modification
Addition of a cyclohexylmethylenedioxy group to the steroid backbone
Potency
Increased compared to prednisolone
Duration of action
Increased compared to prednisolone
Properties
Anti-inflammatory and immunosuppressive
Effective in treating
Autoimmune diseases, allergic reactions, and inflammation
Therapeutic effect
More targeted and potent compared to prednisolone
Applications
Treatment of inflammatory and immune-related disorders
Chemical structure
A synthetic steroid compound with a modified steroid backbone
Molecular weight
Approximately 466.59 g/mol
Stereochemistry
Contains both R and S configurations at the cyclohexylmethylenedioxy group
Functional groups
Hydroxyl groups at the 11β and 21 positions, a carbonyl group at the 3 and 20 positions, and a cyclohexylmethylenedioxy group at the 16α and 17 positions
Solubility
Likely to be soluble in lipophilic solvents due to its steroidal structure
Stability
May be sensitive to light, heat, and moisture, as is common with corticosteroids
Dosage forms
Could be formulated as oral tablets, injectable solutions, or topical creams, depending on the specific application
Side effects
Potential side effects may include those commonly associated with corticosteroids, such as fluid retention, increased blood pressure, and suppression of the immune system
Drug interactions
May interact with other medications, particularly those that have similar mechanisms of action or affect the same physiological pathways
Monitoring
Patients receiving this medication may require regular monitoring of their blood pressure, blood sugar levels, and other health parameters to ensure safe and effective treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 204444-44-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,4,4 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 204444-44:
(8*2)+(7*0)+(6*4)+(5*4)+(4*4)+(3*4)+(2*4)+(1*4)=100
100 % 10 = 0
So 204444-44-0 is a valid CAS Registry Number.
204444-44-0Relevant articles and documents
NOVEL METHOD FOR MANUFACTURING OF CICLESONIDE
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Page/Page column 13; 14, (2013/09/12)
The invention relates to a process for preparing ciclesonide in epimerically pure form, a corticosteroid of formula 1: Ciclesonide is used for the treatment of respiratory complaints.
