1451396-66-9 Usage
Classification
synthetic steroid compound, pregnane derivative
Properties
contains a bromine atom at the 21st position, a hydroxy group at the 11th position, and a cyclohexylmethylenedioxy substituent at the 16th and 17th positions
Pharmacological activity
potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1, involved in the activation of cortisol
Potential pharmaceutical applications
treatment of conditions related to cortisol dysregulation, such as metabolic syndrome, diabetes, and obesity
Importance
valuable compound for further research and development in the field of endocrinology and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 1451396-66-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,1,3,9 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1451396-66:
(9*1)+(8*4)+(7*5)+(6*1)+(5*3)+(4*9)+(3*6)+(2*6)+(1*6)=169
169 % 10 = 9
So 1451396-66-9 is a valid CAS Registry Number.
1451396-66-9Relevant articles and documents
Development of ciclesonide analogues that block SARS-CoV-2 RNA replication
Asakura, Hiroshi,Demizu, Yosuke,Inoue, Takao,Ito, Takahito,Ohoka, Nobumichi,Tsuji, Genichiro,Uema, Masashi,Yanase, Yuta,Yonemitsu, Kenzo
supporting information, (2021/05/03)
Ciclesonide is an inhaled corticosteroid used to treat asthma and is currently undergoing clinical trials for treatment of coronavirus disease 2019 (COVID-19). An active metabolite of ciclesonide, Cic2, was recently reported to repress severe acute respir
NOVEL METHOD FOR MANUFACTURING OF CICLESONIDE
-
, (2013/09/12)
The invention relates to a process for preparing ciclesonide in epimerically pure form, a corticosteroid of formula 1: Ciclesonide is used for the treatment of respiratory complaints.
