204447-02-9

Upstream product

• 322474-21-5 N,N'-bis-Boc-S-methyl-isothiourea 
• 100-46-9 benzylamine 
• 145013-06-5 N,N′-bis(tert-butoxycarbonyl)-N′′-benzylguanidine 
• 216584-22-4 N¹,N²,N³-tris(tert-butoxycarbonyl)guanidine 

Relevant academic research and scientific papers

N,N′,N″-Tri-Boc-guanidine (TBG): a common starting material for both N-alkyl guanidines and amidinoureas

In this Letter, we describe the unexpected reaction pattern of N,N′N″-tri-Boc-guanidine (TBG) with amines at room temperature and under reflux conditions affording N-substituted guanidines and amidinoureas, potentially important compounds with extensive a

Conversion of N,N'-bis(tert-butoxycarbonyl)guanidines to N-(N'-tert-butoxycarbonylamidino)ureas

Surprising aminolysis of bis-Boc-protected guanidines in refluxing THF leads to the corresponding monoBoc substituted amidinoureas.