2045-74-1Relevant academic research and scientific papers
Synthesis of 3,3-dimethyl-2-phenyl-3H-pyrrole from Isopropyl Phenyl Ketoxime and Acetylene: A Side Formation of 4,4-dimethyl-5-phenyl-1-vinyl-2- pyrrolidinone as Clue to the Reaction Mechanism
Shabalin, Dmitrii A.,Glotova, Tatyana E.,Schmidt, Elena Yu.,Ushakov, Igor A.,Mikhaleva, Al'Bina I.,Trofimov, Boris A.
, p. 100 - 101 (2014/04/17)
Isopropyl phenyl ketoxime reacts with acetylene in the KOH/DMSO suspension (atmospheric pressure, 90 °C, 4 h) to afford 3,3-dimethyl-2-phenyl-3H- pyrrole (30%) and 4,4-dimethyl-5-phenyl-1-vinyl-2-pyrrolidinone (5%) that is likely originated from 4,4-dimethyl-5-phenyl-3,4-dihydro-2H-pyrrol-2-ol as the key reaction intermediate.
