204516-37-0Relevant academic research and scientific papers
Preparation of N-arylamines from 2-oxo-7-azobicyclo[4.1.0]heptanes
Barros, M. Teresa,Dey, Suvendu S.,Maycock, Christopher D.,Rodrigues, Paula
supporting information; scheme or table, p. 6263 - 6268 (2012/08/28)
A wide range of N-phenylated secondary amines were prepared directly from 2-oxo-7-azobicyclo[4.1.0]heptanes using 4-nitrobenzoic acid as acid catalyst. The intermediate enol esters could also be isolated under similar conditions. A catalytic cycle is proposed.
The α-halogenation of α,β-unsaturated carbonyls and dihalogenation of alkenes using bisacetoxyiodobenzene/pyridine hydrohalides
Ngatimin, Marsewi,Gartshore, Christopher J.,Kindler, Jeremy P.,Naidu, Sudha,Lupton, David W.
experimental part, p. 6008 - 6011 (2010/03/03)
A procedure for the α-chlorination or bromination of a number of α,β-unsaturated carbonyls, and the dichlorination or bromination of alkenes, is developed using bisacetoxyiodobenzene (BAIB) and the HCl or HBr salt of pyridine. The reaction proceeds in an
A mild preparation of α-halo-α,β-enones from cyclic enones
Righi, Giuliana,Bovicelli, Paolo,Sperandio, Anna
, p. 5889 - 5892 (2007/10/03)
A simple one pot procedure flor the selective transformation of cyclic enones into α-halo-α,β-enones is reported using dimethyldioxirane and metal halides/Amberlyst 15. The method appears particularly appealing for the preparation of labelled molecules for use with the CMIA technique.
Cerium(III) chloride mediated regioselective synthesis of cyclic α- chloro-α,β-enones and α-chloro-β-hydroxy ketones
Montalban, Antonio Garrido,Wittenberg, Lars-Oliver,McKillop, Alexander
, p. 5893 - 5896 (2007/10/03)
Reaction of cyclic α,β-epoxy ketones with Ce(III) chloride under hydrous or anhydrous conditions yields the corresponding cyclic α-chloro- α,β-enones or cyclic α-chloro-β-hydroxy ketones, respectively.
Solvent-free organic reactions on silica gel supports. Facile transformation of epoxides to β-halohydrins with lithium halides
Kotsuki, Hiyoshizo,Shimanouchi, Tomoyasu,Ohshima, Reiji,Fujiwara, Shunsuke
, p. 2709 - 2722 (2007/10/03)
The reaction of epoxides with lithium halides was efficiently promoted on the surface of silica gel in the absence of any solvent to give the corresponding β-halohydrins. The reactivity of lithium halides was shown to follow the order LiI > LiBr >> LiCl, and the reactivity of LiCl was dramatically increased by adding an equivalent amount of water to this system. On the other hand a similar reaction with α,β-epoxyketones produces the α-haloenone derivatives, presumably via halohydrin intermediates. The epoxide-opening reaction of (R)-(+)-styrene oxide was also investigated to clarify the stereochemical features of this reaction.
