204569-87-9Relevant academic research and scientific papers
BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF
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Page/Page column 237, (2019/02/02)
The invention provides novel compounds having the general formula (I): (I) wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.
Multicomponent-multicatalyst reactions (MC)2R: Efficient dibenzazepine synthesis
Tsoung, Jennifer,Panteleev, Jane,Tesch, Matthias,Lautens, Mark
supporting information, p. 110 - 113 (2014/01/23)
A RhI/Pd0 catalyst system was applied to the multicomponent synthesis of aza-dibenzazepines from vinylpyridines, arylboronic acids, and amines in a domino process with no intermediate isolation or purification.
Rh/Pd catalysis with chiral and achiral ligands: Domino synthesis of aza-dihydrodibenzoxepines
Friedman, Adam A.,Panteleev, Jane,Tsoung, Jennifer,Huynh, Vaizanne,Lautens, Mark
supporting information, p. 9755 - 9758 (2013/09/23)
A game of dominoes: A synthetic route to aza-dihydrodibenzoxepines is described, through the combination of a Rh-catalyzed arylation and a Pd-catalyzed C-O coupling in a single pot. For the first time, the ability to incorporate a chiral and an achiral ligand in a two-component, two-metal transformation is achieved, giving the products in moderate to good yields, with excellent enantioselectivities. Copyright
