204570-75-2Relevant academic research and scientific papers
New synthetic analogs of retinoids: Synthesis of aromatic analogs of 9-methylidene- and 13-demethyl-9-methylidene-retinol, -retinal, and ethyl 13-demethyl-9-methylideneretinoate
Valla, Alain,Prat, Virginie,Laurent, Alain,Andriamialisoa, Zo,Cartier, Dominique,Giraud, Michel,Labia, Roger,Potier, Pierre
, p. 3423 - 3427 (2007/10/03)
Aromatic analogs of 9-methylidene and 13-demethyl-9-methylideneretinol, -retinal, and ethyl 13-demethyl-9-methylideneretinoate were synthesized via a new β-methylidene-aldehyde synthon.
Ene diiodo acetals: Stereoselective synthesis of ene hydroxy acetals. Handy access to non conjugated dienals
Bonnet,Ple,Duhamel
, p. 2743 - 2752 (2007/10/03)
After halogen-metal exchange reaction followed by condensation with carbonyl compounds, ene diiodo acetal 1 allow the stereoselective synthesis of ene hydroxy acetals 2 with Z configuration, in a two step procedure. Moreover, after dehydration, the intermediate diene acetals 3-4, via an appropriated hydrolysis procedure, lead to pure non conjugated dienals 5.
