204579-11-3

Basic information

• Product Name: C₁₄H₁₃Cl₃O₃
• Synonyms: C₁₄H₁₃Cl₃O₃
• CAS NO: 204579-11-3
• Molecular Weight: 335.614
• Mol File: 204579-11-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₃Cl₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₃Cl₃O₃(204579-11-3)
• EPA Substance Registry System: C₁₄H₁₃Cl₃O₃(204579-11-3)

Safety Data

• Hazardous Substances Data: 204579-11-3(Hazardous Substances Data)

Upstream product

• 4136-95-2 2,4,6-trichlorobenzoyl chloride 
• 98-89-5 Cyclohexanecarboxylic acid 

Downstream Products

• 15840-96-7 cyclohexyl cyclohexanecarboxylate 
• 70275-61-5 3-phenylpropyl cyclohexanecarboxylate 
• 204579-18-0 Cyclohexanecarbonyl-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-carbamic acid 2-trimethylsilanyl-ethyl ester 
• 204579-13-5 Cyclohexanecarbonyl-((1S,2R)-1,2-dimethoxy-2-phenyl-ethyl)-carbamic acid 2-trimethylsilanyl-ethyl ester 

Relevant articles and documents

An Effective Use of Benzoic Anhydride and Its Derivatives for the Synthesis of Carboxylic Esters and Lactones: A Powerful and Convenient Mixed Anhydride Method Promoted by Basic Catalysts

Various carboxylic esters are obtained at room temperature in excellent yields with high chemoselectivities from nearly equimolar amounts of carboxylic acids and alcohols using 2-methyl-6-nitrobenzoic anhydride with triethylamine by the promotion of a basic catalyst such as 4-(dimethylamino)pyridine. A variety of lactones are also prepared in high yields at room temperature from the corresponding ω-hydroxycarboxylic acids with use of 2-methyl-6-nitrobenzoic anhydride in the presence of 4-(dimethylamino)pyridine. A similar reaction occurs with triethylamine when using a catalytic amount of 4-(dimethylamino)pyridine 1-oxide as an effective promoter for the intramolecular condensation reaction. These methods are successfully applied to the synthesis of erythro-aleuritic acid lactone and an eight-membered-ring lactone moiety of octalactins A and B. The efficiency of the cyclizations is compared to those of other reported lactonizations.

Synthesis of Thiol Esters by Carboxylic Trichlorobenzoic Anhydrides

Thiocarboxylic S-esters were obtained rapidly and in high yields by treating the mixed anhydrides prepared from 2,4,6-trichlorobenzoyl chloride and carboxylic acid, with various types of thiols in the presence of 4-dimethylaminopyridine.