204582-45-6

Basic information

• Product Name: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione
• Synonyms: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione
• CAS NO: 204582-45-6
• Molecular Weight: 626.781
• Mol File: 204582-45-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione(204582-45-6)
• EPA Substance Registry System: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-5-trimethylsilanylethynyl-1H-pyrimidine-2,4-dione(204582-45-6)

Safety Data

• Hazardous Substances Data: 204582-45-6(Hazardous Substances Data)

Upstream product

• 104375-88-4 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine 
• 1066-54-2 trimethylsilylacetylene 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 951-78-0 2'-deoxyuridine 

Downstream Products

• 117626-97-8 5'-O-(4,4'-dimethoxytrityl)-5-(1-phenyl-1H-1,2,3-triazol-4-yl)-2'-deoxyuridine 

Relevant articles and documents

Synthesis of Phosphoramidite Monomers Equipped with Complementary Bases for Solid-Phase DNA Oligomerization

We describe the preparation of two monomers that bear complementary nucleobases at the edges (guanine-2′-deoxycytidine and 2-aminoadenine-2′-deoxyuridine) and that are conveniently protected and activated for solid-phase automated DNA synthesis. We report the optimized synthetic routes leading to the four nucleobase derivatives involved, their cross-coupling reactions into dinucleobase-containing monomers, and their oligomerization in the DNA synthesizer.