204588-75-0

Upstream product

• 22339-69-1 7-(3-carboxypropyl)-1,2,3,4-tetrahydronaphthalen-1-one 
• 204588-72-7 7-[4-hydroxy-1-butynyl]-1,2,3,4-tetrahydronaphthalen-1-one 
• 204588-73-8 7-[4-hydroxybutyl]-1,2,3,4-tetrahydronaphthalen-1-one 
• 144464-65-3 7-Trifluoromethanesulphonyloxy-1,2,3,4-tetrahydronaphthalen-1-one 
• 204588-74-9 7-[3-(benzyloxycarbonyl)propyl]-1,2,3,4-tetrahydronaphthalen-1-one 

Downstream Products

• 204588-76-1 1-{7-[3-(benzyloxycarbonyl)propyl]-1,2,3,4-tetrahydro-1(R,S)-naphthyl}-2,3,4-tri-O-benzyl-α-L-fucopyranose 

Relevant academic research and scientific papers

The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewis(x)

The design and synthesis of a series of analogues of sialyl Lewis(x) (1) which incorporate conformationally rigid tetralin and naphthalene ring systems (2-4) has led to novel compounds which have similar potency to 1 as inhibitors of cell adhesion. Copyright (C) 1998 Elsevier Science Ltd.

The synthesis of novel structural analogues of sialyl Lewis(x)

The synthesis of conformationally rigid tetralin-based mimics of the tetrasaccharide sialyl Lewis(x) are described. Palladium catalysed coupling reactions are employed in the key synthetic steps.