2046-99-3Relevant academic research and scientific papers
Choline-based biodegradable ionic liquid catalyst for Mannich-type reaction
Huan, Peng,Yulin, Hu,Rong, Xing,Dong, Fang
, p. 1855 - 1860 (2016)
A three-component Mannich-type reaction of aromatic aldehydes, ketones, and amines was catalyzed by a novel choline-based acidic ionic liquid. The proposed catalyst was a Lewis-Br?nsted dual acid catalyst as well as water-tolerant. The β-amino carbonyl compounds were obtained at room temperature in reasonable to good yields ranging from 63 to 98%. After the reaction, the catalyst could be recycled and reused for 5 times without obvious decrease of the yield. Further, the catalyst was environment-friendly with a significant biodegradation rate. [Figure not available: see fulltext.]
Br?nsted-Lewis dual acidic ionic liquid immobilized on mesoporous silica materials as an efficient cooperative catalyst for Mannich reactions
Wang, Hong Bo,Yao, Nan,Wang, Long,Hu, Yu Lin
supporting information, p. 10528 - 10531 (2017/10/03)
Novel mesoporous silica supported ILs have been prepared and successfully applied as a heterogeneous catalyst in Mannich reactions. The excellent recyclability of the supported catalyst, mild reaction conditions, good to excellent yields, low catalyst loading, and operational simplicity are the important features of this methodology.
Reusable 1,2,4-triazolium based bronsted acidic room temperature ionic liquids as catalyst for mannich base reaction
Nagarajan, Sankaranarayanan,Kandasamy, Elango
, p. 1507 - 1514,8 (2014/10/15)
Unprecedented examples of 1-alkyl-1,2,4-triazolium methanesulfonate based Bronsted acidic room temperature ionic liquids were synthesized and characterized. Their catalytic activity and efficiency in recyclability and reusability on one pot synthesis of halide substituted β-amino carbonyl compounds are reported. Graphical Abstract: [Figure not available: see fulltext.]
Highly efficient one-pot synthesis, antimicrobial and docking studies of newer β-amino carbonyl derivatives catalyzed by silica sulfuric acid
El-Bayouki,Basyouni,El-Sayed,Tohamy,El-Henawy
, p. 255 - 268 (2013/01/15)
Mannich reaction was applied between 4-fluorobezaldehyde, selected acetophenone and several anilines, catalyzed by silica sulfuric acid for the synthesis of β-amino carbonyl derivatives. Reaction time and yield of the products depended on the nature of ac
