20478-70-0

Basic information

• Product Name: DECANOICACIDHYDRAZIDE
• Synonyms: DECANOICACIDHYDRAZIDE;caprohydrazide;decanehydrazide
• CAS NO: 20478-70-0
• Molecular Formula: C₁₀H₂₂N₂O
• Molecular Weight: 186.3
• Mol File: 20478-70-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 331.2°Cat760mmHg
• Flash Point: 154.1°C
• Appearance: /
• Density: 0.916g/cm³
• Vapor Pressure: 0.000158mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: DECANOICACIDHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DECANOICACIDHYDRAZIDE(20478-70-0)
• EPA Substance Registry System: DECANOICACIDHYDRAZIDE(20478-70-0)

Safety Data

• Hazardous Substances Data: 20478-70-0(Hazardous Substances Data)

Usage

General Description

Decanoic acid hydrazide, also known as decyl hydrazide, is a chemical compound with the molecular formula C10H22N2O. It is a hydrazide derivative of decanoic acid, which is a saturated fatty acid. Decanoic acid hydrazide is commonly used as an intermediate in the production of corrosion inhibitors, plasticizers, and dyes. It can also be used as a fuel additive, a pharmaceutical intermediate, and in the synthesis of various organic compounds. Decanoic acid hydrazide has a low acute toxicity and is generally considered to be safe for use in industrial and laboratory applications.

InChI:InChI=1/C10H22N2O/c1-2-3-4-5-6-7-8-9-10(13)12-11/h2-9,11H2,1H3,(H,12,13)

Upstream product

• 110-42-9 Methyl decanoate 
• 334-48-5 1-decanoic acid 
• 110-38-3 decanoic acid ethyl ester 

Downstream Products

• 114953-92-3 3-Nonyl-5-phenyl-1H-[1,2,4]triazole 
• 111-11-5 methyl octanate 
• 124-07-2 Octanoic acid 
• 51707-21-2 3-(decanoylhydrazono-methyl)-rifamycin 
• 1290139-27-3 decanoic acid [4-oxo-2-(4-hydroxy-3,5-dimethoxyphenyl)-thiazolidin-3-yl]amide 
• 346720-65-8 decanoic acid (2-nitrobenzylidene)hydrazide 
• 1316243-25-0 decanoic acid [4-oxo-2-(2-nitrophenyl)-thiazolidin-3-yl]amide 
• 1316243-31-8 decanoic acid [4-oxo-2-(4-(N,N-dimethylamino)phenyl)-thiazolidin-3-yl]amide 
• 525564-60-7 decanoic acid (4-dimethylaminobenzylidene)hydrazide 
• 101739-63-3 decanoic acid (2-hydroxybenzylidene)hydrazide 
• 1316243-30-7 decanoic acid [4-oxo-2-(2-hydroxyphenyl)-thiazolidin-3-yl]amide 
• 1290139-26-2 decanoic acid [4-oxo-2-(4-methoxyphenyl)-thiazolidin-3-yl]amide 
• 1290139-23-9 decanoic acid [4-oxo-2-(3-nitrophenyl)-thiazolidin-3-yl]amide 
• 1290139-25-1 decanoic acid [4-oxo-2-(4-chlorophenyl)-thiazolidin-3-yl]amide 

Relevant articles and documents

Concise total synthesis of hydrazidomycin A, a rare hydrazide metabolite of streptomyces atratus

Hydrazidomycins A-C and elaiomycins B-C represent a family of unusual, naturally occurring enehydrazides produced by Streptomyces sp. A general synthetic approach to access these densely functionalized hydrazine derivatives is exemplified by the first total synthesis of hydrazidomycin A. The modular synthesis involves a ruthenium-catalyzed hydroamidation of an alkyne and a hydrazide-derived phthalimide to yield predominantly the Z-configured enehydrazide. Copyright

Lipophilic gold(I) complexes with 1,3,4-oxadiazol-2-thione or 1,3-thiazolidine-2-thione moieties: synthesis and their cytotoxic and antimicrobial activities

Novel lipophilic gold(I) complexes containing 1,3,4-oxadiazol-2-thione or 1,3-thiazolidine-2-thione derivatives were synthesized and characterized by IR, high resolution mass spectrometry, and 1H, 13C 31P NMR. The cytotoxicity of the compounds was evaluated considering cisplatin and/or auranofin as reference in different tumor cell lines: colon cancer (CT26WT), metastatic skin melanoma (B16F10), breast adenocarcinoma (MCF-7), cervical carcinoma (HeLa), glioblastoma (M059?J). Normal human lung fibroblasts (GM07492-A) and kidney normal cell (BHK-21) were also evaluated. The gold(I) complexes were more active than their respective free ligands and cisplatin. Furthermore, antibacterial activity was evaluated against Gram-positive bacteria Staphylococcus aureus ATCC 25213, Staphylococcus epidermidis ATCC 12228 and Gram-negative bacteria Escherichia coli ATCC 11229 and Pseudomonas aeruginosa ATCC 27853 and expressed as the minimum inhibitory concentration (MIC). The complexes exhibited lower MIC values when compared to the ligands and chloramphenicol against Gram-positive bacteria and Gram-negative bacteria. Escherichia coli was sensitive one to the action of gold(I) complexes.

Synthesis of some novel 2,5-disubstituted thiazolidinones from a long chain fatty acid as possible anti-inflammatory, analgesic and hydrogen peroxide scavenging agents

Some new decanoic acid [2,5-disubstituted-4-oxo-thiazolidin-3-yl]amides (6a-j) have been synthesised by the condensation of decanoic acid hydrazide with various aromatic aldehydes to yield the Schiff's bases. Cyclocondensation of the Schiff's bases with thioglycollic acid afforded 4-thiazolidinone derivatives. The structures of the newly synthesised compounds were confirmed by analytical and spectral methods. The anti-inflammatory, analgesic and antioxidant activity of the title compounds were evaluated. Compound 6j exhibited 44.84 % inhibition of inflammation and was the most potent anti-inflammatory agent of the series whereas compound 6f demonstrated the most potent analgesic activity (69.82% inhibition of writhing) followed by compounds 6e and 6g. All the synthesised compounds exhibited a potent antioxidant activity.