2048-37-5

Upstream product

• 1504-78-5 3-phenylquinoxaline-2(1H)-one 
• 74-88-4 methyl iodide 
• 25148-68-9 N-methylbenzene-1,2-diamine dihydrochloride 
• 611-73-4 Benzoylformic acid 
• 119867-75-3 ethyl methyl(phenyl)hydrazono(phenyl)acetate 
• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 98-80-6 phenylboronic acid 
• 25160-82-1 1-methyl-3-phenyl-3,4-dihydroquinoxalin-2(1H)-one 
• 66003-76-7 Diphenyliodonium triflate 
• 6293-66-9 diphenyliodonium p-toluenesulfonate 
• 591-50-4 iodobenzene 
• 530-48-3 1,1-Diphenylethylene 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 25160-82-1 1-methyl-3-phenyl-3,4-dihydroquinoxalin-2(1H)-one 
• 112828-53-2 4-Methyl-1,1,2a-triphenyl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one 
• 112828-52-1 1,4-Dimethyl-1,2a-diphenyl-2,2a-dihydro-1H,4H-azeto[1,2-a]quinoxalin-3-one 
• 1255772-54-3 (+)-(S)-1-methyl-3-phenyl-3,4-dihydroquinoxalin-2(1H)-one 
• 102549-65-5 4-methyl-N-(2-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide 

Relevant academic research and scientific papers

Metal-free visible-light-initiated direct C3 alkylation of quinoxalin-2(1: H)-ones and coumarins with unactivated alkyl iodides

We report, for the first time, a visible-light-promoted direct C3 alkylation of quinoxalin-2(1H)-ones and coumarins using readily accessible unactivated alkyl iodides as alkylation reagents. By applying this new approach, a broad range of valuable 3-alkylated quinoxalin-2(1H)-ones and coumarins (55 examples) can be facilely obtained at room temperature, thus showing the wide utility of this protocol. Notably, this practical reaction occurs under metal- and external photocatalyst-free conditions and exhibits a broad substrate scope and high functional-group tolerance.

Aryl acyl peroxides for visible-light induced decarboxylative arylation of quinoxalin-2(1: H)-ones under additive-, metal catalyst-, and external photosensitizer-free and ambient conditions

Aryl radicals were generated for the first time from cheap and easily available aryl acyl peroxides in eco-friendly ethyl acetate under ambient conditions and visible-light illumination in the absence of any additive, metal catalyst, or external photosensitizer. The present arylation of quinoxalin-2(1H)-ones was chemo- and regioselective, and provided good access to various 3-arylquinoxalin-2(1H)-ones. This journal is

Visible-light-induced C[sbnd]H arylation of quinoxalin-2(1H)-ones in H2O

An efficient visible-light-induced C[sbnd]H arylation of quinoxalin-2(1H)-ones in H2O is developed, which has the advantages of mild reaction conditions, environmental friendliness and good functional group tolerance. This strategy provides a s

Molecular oxygen-mediated selective hydroxyalkylation and alkylation of quinoxalin-2(1H)-ones with alkylboronic acids

Herein, an efficient molecular oxygen-mediated method for the selective hydroxyalkylation and alkylation of quinoxalin-2(1H)-ones with alkylboronic acids under transition-metal free conditions has been developed. This strategy demonstrates a broad scope of quinoxalin-2(1H)-ones and alkylboronic acids, giving 3-hydroxyalkylquinoxalin-2(1H)-ones and 3-alkylquinoxalin-2(1H)-ones in moderate-to-good yield. Control experiments reveal that a radical pathway is involved.

3-aryl-2(1H)-quinoxalinone and synthesis method thereof

The invention discloses 3-aryl-2(1H)-quinoxalinone and a synthesis method thereof. According to the synthesis method, 2(1H)-quinoxalinone and aryl acyl peroxide are used as raw materials, acetone is used as a solvent at normal temperature, an LED lamp is used as a light source, and 3-aryl-2(1H)-quinoxalinone is synthesized under the irradiation of the LED lamp. The method avoids using any metal, photocatalyst or additive, and has the advantages of mild reaction conditions, simple experimental operation, good reaction selectivity, high product yield, easy product separation and the like.

Direct C-H arylation of quinoxalinones with aryl acylperoxides under catalyst-free condition

A simple and novel method for the direct C-H arylation of quinoxalinones with aryl acylperoxides has been developed. This reaction proceeded smoothly through a radical process under catalyst-free condition, giving the target products in moderate good yields. Such strategy provides a simple and green alternative for the synthesis of 3-arylquinoxalinones.

Palladium-catalyzed direct Hiyama arylation of quinoxalin-2(1H)-ones with aryl siloxanes in water

An efficient method for palladium-catalyzed direct Hiyama coupling of various quinoxalin-2(1H)-ones with aryl siloxanes has been developed. The protocol provides a convenient access to a variety of useful C3-arylated 1-methylquinoxalin-2(1H)-one derivatives in reasonable yields by using low cost water as a solvent and oxygen as an oxidant.

K2S2O8 mediated C-3 arylation of quinoxalin-2(1H)-ones under metal-, photocatalyst- And light-free conditions

Two facile and effective C-3 arylation protocols of quinoxalin-2(1H)-ones with arylhydrazines and aryl boronic acids respectively via free radical cross-coupling reactions under metal-, photocatalyst- and light-free conditions have been unveiled. K2

Direct decarboxylative C[sbnd]H 3-arylation of quinoxalin-2(H)-ones with aryl acyl peroxides leading to 3-arylquinoxalin-2(1H)-ones

A facile and direct decarboxylative C[sbnd]H 3-arylation of quinoxalin-2(H)-ones with aryl acyl peroxides has been developed for the synthesis of 3-arylquinoxalin-2(1H)-ones under simple heating conditions. The present methodology provides a simple and highly efficient approach to various 3-arylquinoxalin-2(1H)-ones in high yields without the use of any catalyst and additives.

Photocatalytic synthesis method of 3-aryl-N-methylquinoxalin-2(1H)-one compound

The invention discloses a photocatalytic synthesis method of a 3-aryl-N-methylquinoxalin-2(1H)-one compound, wherein the method comprises the steps: carrying out one-pot reaction on an N-methylquinoxalin-2(1H)-one compound and an aryl formyl peroxide comp