204909-76-2

Upstream product

• 204909-71-7 (3aS,6S,6aS)-6-(tert-Butyl-dimethyl-silanyloxy)-tetrahydro-furo[3,2-b]furan-3-one 
• 204909-72-8 tert-Butyl-dimethyl-((3S,3aS,6aR)-6-methylene-hexahydro-furo[3,2-b]furan-3-yloxy)-silane 
• 204909-70-6 (3R,3aR,6S,6aS)-6-((tert-butyldimethylsilyl)oxy)hexahydrofuro[3,2-b]furan-3-ol 
• 98-88-4 benzoyl chloride 
• 204909-75-1 [(3R,3aR,6S,6aS)-6-(tert-Butyl-dimethyl-silanyloxy)-hexahydro-furo[3,2-b]furan-3-yl]-methanol 

Downstream Products

• 204909-84-2 Benzoic acid (3S,3aR,5R,6R,6aS)-5-(6-chloro-purin-9-yl)-6-iodo-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-85-3 Benzoic acid (3S,3aR,5R,6aR)-5-(6-chloro-purin-9-yl)-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-81-9 Benzoic acid (3S,3aR,5R,6R,6aS)-5-(4-acetylamino-2-oxo-2H-pyrimidin-1-yl)-6-iodo-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-82-0 Benzoic acid (3S,3aR,5R,6aR)-5-(4-acetylamino-2-oxo-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-78-4 Benzoic acid (3S,3aR,5R,6R,6aS)-6-iodo-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-79-5 Benzoic acid (3S,3aR,5R,6aR)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 
• 204909-69-3 Benzoic acid (3S,3aR,6aR)-1-(2,3,3a,6a-tetrahydro-furo[3,2-b]furan-3-yl)methyl ester 
• 204909-77-3 Benzoic acid (3S,3aR,6S,6aR)-6-hydroxy-hexahydro-furo[3,2-b]furan-3-ylmethyl ester 

Relevant academic research and scientific papers

Concise and stereospecific synthesis of novel bicyclic dideoxynucleosides as potential antiviral agents

A novel class of dideoxynucleosides containing a bicyclic sugar moiety, structurally related to the natural griseolic acids, was synthesized starting from the stereochemically defined compound, 1,4:3,6-dianhydro-D-glucitol. The key intermediate in the synthesis was a [3.3.0] fused bicyclic glycal. Glycosylation of this compound with nucleobase proceeded both regiospecifically and stereospecifically in the presence of an auxiliary agent, N-iodosuccinamide. Changes in stereochemistry during the synthesis was monitored by optical rotation data and confirmed by both 1D and 2D NMR experiments. The synthetic approach described possesses general usefulness.