20495-99-2

Basic information

• Product Name: 3-chloropropionic anhydride
• Synonyms: 3-chloropropionic anhydride
• CAS NO: 20495-99-2
• Molecular Weight: 199.034
• Mol File: 20495-99-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-chloropropionic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloropropionic anhydride(20495-99-2)
• EPA Substance Registry System: 3-chloropropionic anhydride(20495-99-2)

Safety Data

• Hazardous Substances Data: 20495-99-2(Hazardous Substances Data)

Upstream product

• 7782-50-5 chlorine 

Downstream Products

• 25255-95-2 3-Chloro-N-(3-propionylamino-phenyl)-propionamide 
• 25256-20-6 N-[3-(3-Chloro-propionylamino)-phenyl]-isobutyramide 
• 25227-89-8 1,3-bis-(3-chloro-propionylamino)-benzene 
• 53919-74-7 5-(2-Chloroethyl)-3-phenyl-1,2,4-oxadiazole 
• 20495-98-1 β-chloropropionyl-2-amino-4-phenylthiazole 

Relevant articles and documents

Halogenolysis of a nickelalactone complex produces β-halo-anhydrides

Nickelalactone complex [(dppe)Ni{κ2-C,O-CH2CH2C(=O)O}] {dppe = 1,2-bis(diphenylphosphino)ethane} reacts with halogens to form 3-halo-propionic anhydrides, [(dppe)NiX2], and [(dppeO2)3Ni][NiX4] (X = Cl, Br, I). Studies of model complexes [(dppe)Ni(O2CtBu)2] and [(dppe)NiBr(O2CtBu)] suggest that oxidation to NiIII and P-O reductive elimination are key steps in this reaction.