20498-72-0Relevant academic research and scientific papers
Heterogeneous visible-light-induced Meerwein hydration reaction of alkenes in water using mpg-C3N4 as a recyclable photocatalyst
Wang, Jingjing,Xue, Linshuang,Hong, Mei,Ni, Bangqing,Niu, Tengfei
, p. 411 - 416 (2020/02/13)
A green and efficient visible light induced Meerwein hydration reaction of alkenes in aqueous medium using mpg-C3N4 as a recyclabe photocatalyst has been disclosed. This protocol provides a direct approach for the preparation of racemic alcohols via a free radical mechanism. Water acted as both a solvent and a reagent without any additives or co-solvents. The metal-free heterogeneous semiconductor is found to be fully recyclable at least 5 times without any significant reduction in activity. The Meerwein hydration reaction has an excellent substrate scope and gave the desired products in moderate to high yields. Furthermore, this reaction could be carried out under solar light irradiation and is applicable for large-scale reactions with satisfactory results.
Thermally Induced Carbohydroxylation of Styrenes with Aryldiazonium Salts
Kindt, Stephanie,Wicht, Karina,Heinrich, Markus R.
supporting information, p. 8744 - 8747 (2016/07/21)
The radical carbohydroxylation of styrenes with aryldiazonium salts has been achieved under mild thermal conditions. A broad range of aryldiazonium salts was tolerated, and the reaction principle based on a radical–polar crossover mechanism could be exten
Antifungal agents. 5. Chloro and amino derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane with potent antifungal activities
Artico, M.,Massa, S.,Santo, R. Di,Costi, R.,Retico, A.,et al.
, p. 715 - 720 (2007/10/02)
Various derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane have been synthesized and tested against Candida albicans and Candida spp.In vitro essays showed chloro and amino derivatives to be as active as miconazole and bifonazole and more potent than ketoconazole.Structure-activity relationships of the new imidazole antifungal agents are discussed.antifungal agents/estrogen-like imidazoles/1,2-diaryl-1-(1H-imidazol-1-yl)ethane derivatives
Ceric Ammonium Nitrate Oxidative-Cleavage Reaction of Some Lignin Model Compounds: Role of the Benzylic Hydroxyl Group
Fisher, Thomas H.,Dershem, Stephen M.,Schultz, Tor P.
, p. 1504 - 1507 (2007/10/02)
A series of β-1 lignin model compounds was synthesized and then oxidized with ceric ammonium nitrate (CAN) in aqueous acetonitrile.The compounds studied were 1,2-diarylethanols with either a p-hydroxy (1a-e) or a p-methoxy (2a-e) on the 1-ring and the following para substituents on the 2-ring: (a) H, (b) Cl, (c) Me, (d) OMe, and (e) NO2.Reactions of p-hydroxyl compounds 1a-e with CAN resulted in the formation of a red cerium complex that did not oxidize under the conditions of the reaction.In contrast all of the methoxy compounds 2a-e were rapidly oxidized by CAN atroom temperature to give p-anisaldehyde in near quatitative yield.The relative rates of these oxidative-cleavage reactions were found to be 0.11, 0.16, 1.00, 1.58, and 2.37 for the 1,2-diarylethanols 2e, 2b, 2a, 2c, and 2d, respectively.A Hammett treatment of this data revealed an excellent correlation with ?(ρ = -1.24).Methylation of the benzylic hydroxy group of 2a gave 1-methoxy-1-(4-methoxyphenyl)-2-phenylethane, which was found to be inert to CAN oxidation.
