205-39-0Relevant articles and documents
A chemo- And regioselective Pd(0)-catalyzed three-component spiroannulation
Wu, Jiaoyu,Bai, Lu,Han, Lingbo,Liu, Jingjing,Luan, Xinjun
, p. 1117 - 1120 (2021)
A chemo- and regioselective Pd(0)-catalyzed spiroannulation has been successfully developed. The key feature of this method is the use of readily available 1,2-dihaloarenes, alkynes and 2-naphthols for the rapid assembly of spirocarbocyclic molecules. Mechanistic studies revealed that this domino reaction proceeded through a cascade of oxidative addition to Pd(0), alkyne migratory insertion, and 2-naphthol-facilitated dearomatizing [4+1] spiroannulation.
Helicene synthesis by Br?nsted acid-catalyzed cycloaromatization in HFIP [(CF3)2CHOH]
Fujita, Takeshi,Shoji, Noriaki,Yoshikawa, Nao,Ichikawa, Junji
, p. 396 - 403 (2021/03/20)
A facile synthesis of carbo- and heterohelicenes was achieved via tandem cycloaromatization of bisacetal precursors, which were readily prepared through C-C bond formation by Suzuki-Miyaura coupling. This cyclization was efficiently realized by a catalytic amount of trifluoromethanesulfonic acid (TfOH) in a cation-stabilizing solvent, 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP), which readily allowed gram-scale syntheses of higher-order helicenes, double helical helicenes, and heterohelicenes.
Naphthylbenzofuran derivative and preparation method thereof
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Paragraph 0028; 0030, (2018/07/06)
The invention belongs to the technical field of organic synthesis and particularly relates to a naphthylbenzofuran derivative and a preparation method thereof. The preparation method comprises that a1-bromo-2-naphthol derivative and a phenylboronic acid derivative undergo a reaction to produce an intermediate, the intermediate undergoes an intramolecular dehydration and ring-forming reaction under the action of cesium carbonate to produce the naphthylbenzofuran derivative. The naphthylbenzofuran and its derivative can be used as important synthesis intermediates of functional organic semiconductors such as organic electroluminescence devices, organic solar batteries, organic lasers, optical switches and ion detectors. The modified compound can be used as light-emitting host and guest materials, a carrier transport material and an exciton-blocking material in organic electroluminescent devices. The invention can provide the naphthylbenzofuran derivative with the advantages of simple processes, low synthesis condition requirements, high synthesis yield, industrial large-scale production feasibility and good economic benefits and the preparation method thereof.