20503-93-9Relevant academic research and scientific papers
Catalyst-Free Regioselective [3+2] Cycloadditions of α,β-unsaturated N-arylnitrones with Alkenes to Access Functionalized Isoxazolidines: A DFT Study
Ghosh, Arnab,Mane, Manoj V.,Rode, Haridas B.,Patil, Siddappa A.,Sridhar, Balasubramanian,Dateer, Ramesh B.
supporting information, p. 899 - 903 (2020/03/03)
The catalyst-free regioselective [3+2]-cycloaddition of α,β-unsaturated N-arylnitrones with alkenes are developed. The series of synthetically important functionalized isoxazolidines are prepared in good to excellent yields by step economic pathway under ligand and transition-metal-free conditions. The regioselective cycloaddition pathway supported by control experiment and computational study.
Microwave induced 1,3-Dipolar cycloaddition reactions of nitrones
Baruah, Bipul,Prajapati, Dipak,Boruah, Anima,Sandhu, Jagir S.
, p. 2563 - 2567 (2007/10/03)
1,3-Dipolar cycloaddition reactions involving unreactive nitrones have been carried out successfully under microwave irradiations. The reaction of nitrones I and alkene 2 proceeded regiospecifically at atmospheric pressure and the corresponding isoxazolidines 3 were obtained in high yields.
