205052-93-3Relevant articles and documents
Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts
Horan, Alexandra M.,Duong, Vincent K.,McGarrigle, Eoghan M.
supporting information, p. 9089 - 9093 (2021/11/30)
Herein are reported ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages, including 2,4′-, 2,3′-, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes. The methodology was successfully applied to the synthesis of the natural products caerulomycin A and E.
First Syntheses of Caerulomycin E and Collismycins A and C. A New Synthesis of Caerulomycin A
Trécourt, Fran?ois,Gervais, Bruno,Mongin, Olivier,Gal, Catherine Le,Mongin, Florence,Quéguiner, Guy
, p. 2892 - 2897 (2007/10/03)
Caerulomycins produced by Streptomyces caeruleus, and collismycins more recently isolated from Streptomyces species, are bipyridinic molecules endowed with antibiotic and cytotoxic activities. The first syntheses of caerulomycin E (1), as well as new synt
