20511-09-5Relevant academic research and scientific papers
Regioselective C-H activation and sequential C-C and C-O bond formation reactions of aryl ketones promoted by an yttrium carbene
Mills, David P.,Soutar, Lyndsay,Lewis, William,Blake, Alexander J.,Liddle, Stephen T.
supporting information; experimental part, p. 14379 - 14381 (2010/12/25)
Rare earth carbenes exclusively exhibit Wittig-type reactivity with carbonyl compounds to afford alkenes. Here, we report that yttrium carbenes can effect regioselective ortho-C-H activation and sequential C-C and C-O bond formation reactions of aryl ketones to give iso-benzofurans and hydroxymethylbenzophenones. With MeCOPh, cyclotetramerization occurs giving a substituted cyclohexene. This demonstrates new rare earth carbene reactivity which complements existing Wittig-type reactivity.
Aldol Reactions Promoted by Diethylzinc; the X-ray Crystal Structure and Stereochemistry of Dypnopinacol.
Chaloner, Penny A.,Hitchcock, Peter B.,Langadianou, Eugenia,Readey, Michael J.
, p. 6037 - 6038 (2007/10/02)
Diethylzinc reacted with acetophenone to give the aldol dimer, 1,3-diphenyl-2-butene-1-one together with small amounts of dypnopinacol 1-(2-hydroxy-6-methyl-2,4,6-triphenylcyclohex-3-enyl)-1-phenylmethanone.The structure of dypnopinacol was established in an X-ray diffration study.Key Words: Aldol; Diethylzinc, Conjugate reduction; Dypnopinacol
