205171-05-7 Usage
General Description
6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine, also known as 6-Cl-2-Me-Ribosyl-Purine, is a synthetic analog of adenosine that has been found to exhibit antiviral and antitumor activities. This chemical is a purine nucleoside analog that has been studied for its potential use in the treatment of various viral infections, including HIV and herpes simplex virus. It has also been investigated for its potential anti-cancer properties, particularly in the treatment of leukemia and other lymphoid malignancies. Studies have shown that 6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine works by inhibiting the replication of viral DNA and RNA, as well as disrupting the synthesis of DNA and RNA in cancer cells, making it a promising candidate for the development of new antiviral and anticancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 205171-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,1,7 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 205171-05:
(8*2)+(7*0)+(6*5)+(5*1)+(4*7)+(3*1)+(2*0)+(1*5)=87
87 % 10 = 7
So 205171-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H13ClN4O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3/t5-,7-,10-,11-/m1/s1
205171-05-7Relevant articles and documents
2'-C-Methyl analogues of selective adenosine receptor agonists: Synthesis and binding studies
Franchetti, Palmarisa,Cappellacci, Loredana,Marchetti, Stefano,Trincavelli, Letizia,Martini, Claudia,Mazzoni, Maria R.,Lucacchini, Antonio,Grifantini, Mario
, p. 1708 - 1715 (1998)
2'-C-Methyl analogues of selective adenosine receptor agonists such as (R)-PIA, CPA, CCPA, NECA, and IB-MECA were synthesized in order to further investigate the subdomain that binds the ribose moiety. Binding affinities of these new compounds at A1
