2'-C-Methyl analogues of selective adenosine receptor agonists: Synthesis and binding studies

DOI: 10.1021/jm9707737

Source and publish data:

Journal of Medicinal Chemistry p. 1708 - 1715 (1998)

Update date:2022-08-03

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Authors:

Franchetti, Palmarisa

Cappellacci, Loredana

Marchetti, Stefano

Trincavelli, Letizia

Martini, Claudia

Mazzoni, Maria R.

Lucacchini, Antonio

Grifantini, Mario

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Article abstract of DOI:10.1021/jm9707737

2'-C-Methyl analogues of selective adenosine receptor agonists such as (R)-PIA, CPA, CCPA, NECA, and IB-MECA were synthesized in order to further investigate the subdomain that binds the ribose moiety. Binding affinities of these new compounds at A_1<

Full text of DOI:10.1021/jm9707737

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