205250-14-2Relevant academic research and scientific papers
PhI(OCOCF3)2-Mediated Cyclization of o -(1-Alkynyl)benzamides: Metal-Free Synthesis of 3-Hydroxy-2,3-dihydroisoquinoline-1,4-dione
Yang, Chao,Zhang, Xiang,Zhang-Negrerie, Daisy,Du, Yunfei,Zhao, Kang
, p. 5320 - 5328 (2015/05/27)
The synthesis of an undocumented skeleton of 3-hydroxy-2,3-dihydroisoquinoline-1,4-diones has been discovered and reported. The reaction consists of an intramolecular cyclization of o-(1-alkynyl)benzamides in MeCN/H2O, mediated by metal-free, h
Reaction of 2-alkynylbenzoyl cyanides with carboxylic acids producing functionalized indenones
Shimizu, Hiroshi,Murakami, Masahiro
experimental part, p. 1817 - 1820 (2009/04/16)
2-Alkynylbenzoyl cyanides react with carboxylic acids via a cyclic allene intermediate to produce 2-acylamino-3-acylindenones in good yield. The high reactivity of the 2-acylamino moiety of the product for a substitution reaction can be utilized for the s
An Efficient Stereospecific Preparation of (Z)-3-Methylidene-selenophthalides and (Z)-3-Methylidenetellurophthalides [1]
Sashida, Haruki,Kawamukai, Atsushi
, p. 165 - 167 (2007/10/03)
(Z)-3-Methylideneselenophthalides 5A and (Z)-3-methylidenetellurophthalides 5B were easily prepared by the regioselective and stereoselective reaction of 2-ethynylbenzoyl chlorides 3 with sodium hydroselenide and sodium hydrotelluride in good yields, resp
