205308-02-7Relevant academic research and scientific papers
1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors
Desideri, Nicoletta,Fioravanti, Rossella,Proietti Monaco, Luca,Biava, Mariangela,Yanez, Matilde,Ortuso, Francesco,Alcaro, Stefano
, p. 91 - 100 (2013/03/13)
A series of (2E,4E)-1-(2-hydroxyphenyl)-5-phenylpenta-2,4-dien-1-ones (3a-r) and (2Z,4E)-3-hydroxy-1-(2-hydroxyphenyl)-5-phenylpenta-2,4-dien-1-ones (6a-l) were synthesized and evaluated in vitro as inhibitors of the two human Monoamine oxidase (hMAO) iso
Efficient syntheses of new polyhydroxylated 2,3-diaryl-9H-xanthen-9-ones
Santos, Clementina M. M.,Silva, Artur M. S.,Cavaleiro, Jose A. S.
experimental part, p. 2642 - 2660 (2009/10/23)
A large number of hydroxylated 2,3-diaryl-9/i-xanthen-9ones have been synthesised by two different approaches, starting either from 3-brom.o-2-m.elhyl-4H-ch:rom.en-4-one or from. (E)-3-brom.o-2-styryl-4H-chrom. en-4-ones. The former method involves Heck r
A novel and efficient route for the synthesis of hydroxylated 2,3-diarylxanthones
Santos, Clementina M. M.,Silva, Artur M. S.,Cavaleiro, José A. S.
, p. 3113 - 3116 (2008/09/19)
A novel, efficient and general route for the synthesis of hydroxylated 2,3-diarylxanthones is described. 3-Bromo-2-styryl-chromone, the key intermediate of this synthesis, is obtained by a Baker-Venkataraman rearrangement of the appropriate 2′-cinnamoylox
Synthesis of 3-alkenyl-2-arylchromones and 2,3-dialkenylchromones via acid-catalysed retro-Michael ring opening of 3-acylchroman-4-ones
Clarke, David S.,Gabbutt, Christopher D.,Hepworth, John D.,Heron, B. Mark
, p. 5515 - 5519 (2007/10/03)
3-Acylchromones and 3-acylflavones, readily available by acylation of 2′-hydroxydibenzoylmethane with acid anhydrides in the presence of base, undergo efficient conjugate reduction with NaBH4 in pyridine to give the corresponding chroman-4-ones/flavanones in high yields. The reduction is both regio- and chemoselective. Treatment of the chroman-4-ones with MeSO 3H generates the 3-alkenyl-2-arylchromones by a dehydrative rearrangement initiated by retro-Michael cleavage of the pyranone ring. This reduction-rearrangement sequence can be extended to 2-alkyl-3-alkenoylchromones to generate 3-alkenyl-2-styrylchromones, the first examples of 2,3-dialkenylchromones.
The synthesis of various cycloalkana[d]xanthones and conversion of the cyclohexa-analogue to a 7,7a-dimethylcyclohexa-[d]xanthene
Letcher, Roy M.,Yue, Tai-Yuen,Chiu, Kwei-Fung,Kelkar, Avijit S.,Cheung, Kung-Kai
, p. 3267 - 3276 (2007/10/03)
The synthesis of cyclo-penta-, -hexa- and -hepta-[d]xanthones 5 from (E)-(2-hydroxyphenyl)-5-arylpent-4-ene-1,3-diones 4, cycloalkanones and pyrrolidine is described. Reactions to modify 5 in an attempt to synthesize analogues of the five naturally occurr
Synthesis of 4-Aryl-3-(2-chromonyl)-2-pyrazolines by the 1,3-Dipolar Cycloaddition of 2-Styrylchromones with Diazomethane
Pinto, Diana C.G.A.,Silva, Artur M.S.,Almeida, Lucia M.P.M.,Cavaleiro, Jose A.S.,Levai, Albert,Patonay, Tamas
, p. 217 - 224 (2007/10/03)
The first reported 1,3-dipolar cycloaddition of 2-styrylchromones with diazomethane afforded 4-aryl-3-(2-chromonyl)-2-pyrazolines. However, 3-aryl-4-(2-chromonyl)-1-pyrazolines have been also found as minor products of this reaction. These two series of p
