20531-84-4

Upstream product

• 141-97-9 ethyl acetoacetate 
• 94-70-2 ortho-phenitidine 

Downstream Products

• 132576-96-6 4-[(2-Ethoxy-phenyl)-hydrazono]-5-methyl-2-(pyridine-4-carbonyl)-2,4-dihydro-pyrazol-3-one 
• 112517-61-0 2-(3,5-Dinitro-benzoyl)-4-[(2-ethoxy-phenyl)-hydrazono]-5-methyl-2,4-dihydro-pyrazol-3-one 
• 84384-55-4 2-[2-(2,4-Dinitro-phenyl)-acetyl]-4-[(2-ethoxy-phenyl)-hydrazono]-5-methyl-2,4-dihydro-pyrazol-3-one 
• 131628-05-2 3-{4-[(2-Ethoxy-phenyl)-hydrazono]-3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl}-N-naphthalen-2-yl-3-oxo-propionamide 
• 1430402-58-6 C₂₀H₁₉N₅O₂S₂ 
• 1430402-91-7 C₂₃H₂₃N₅O₃S 
• 1430402-59-7 C₂₅H₂₇N₅O₂S 
• 1430402-74-6 C₂₁H₂₀N₆O₂ 
• 82506-38-5 C₁₃H₁₆N₆O₂ 
• 132577-13-0 4-[(2-Ethoxy-phenyl)-hydrazono]-5-methyl-2-phthalazin-1-yl-2,4-dihydro-pyrazol-3-one 

Relevant academic research and scientific papers

PYRAZOL-3-ONES THAT ACTIVATE PRO-APOPTOTIC BAX

This application features pyrazol-3-one compounds that activate pro-apoptotic BAX. Also featured are methods of using such compounds, e.g., for the treatment or prevention of diseases, disorders, and conditions associated with deregulated apoptosis of cells (e.g., insufficient apoptosis of diseased or damaged cells or essentially the absence of apoptosis of diseased or damaged cells).