20532-31-4

Upstream product

• 19301-35-0 benzo[b]thiophen-5-ol 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 98589-46-9 5-aminobenzo[b]thiophene-2-carboxylic acid 
• 95094-87-4 5-hydroxy benzo[b]thiophene-2-carboxylic acid 
• 6345-55-7 5-nitrobenzo[b]thiophene-2-carboxylic acid 

Downstream Products

• 101494-83-1 3-bromo-1-benzo[b]thiophen-5-ol 

Relevant academic research and scientific papers

GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS

Disclosed are compositions comprising (a) a GPR40 agonist and (b) an SGLT2 inhibitor, and methods for treating of disorders that are affected by the modulation of the GPR40 receptor and SGLT2 transporter. Such GPR40 compounds are represented by Formula (I) as follows: wherein ring W, R1, R2, R3, R5, R6, A, and Z, are defined herein.

SUBSTITUTED BENZOTHIOPHENYL DERIVATIVES AS GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I) wherein R1, R2, R3, R5, R6, W, and A are defined herein.

Benzothiophene derivative compounds process of preparation and use thereof

This invention provides new benzothiophene derivatives of general formula (I) and a process for preparing them, the corresponding compositions and their use for manufacturing a medicine for the treatment of neurological disorders. These new compounds behave as serotonin reuptake inhibitors and show high affinity towards the 5-HT1A receptor.