20532-33-6

Basic information

• Product Name: 5-CHLOROBENZOTHIOPHENE
• Synonyms: 5-CHLOROBENZOTHIOPHENE;5-Chlorobenzo[b]thiophene;5-chlorine Benzothiophene;5-Chlorobenzothiophene ,98%;5-Chlorothionaphthene;6-chlorobenzo[b]thiophene;5-chloro-1-benzothiophene;5-chlorine thiofuran-2-carboxylic acid
• CAS NO: 20532-33-6
• Molecular Formula: C₈H₅ClS
• Molecular Weight: 168.64
• Mol File: 20532-33-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 261.5 °C at 760 mmHg
• Flash Point: 147.6 °C
• Appearance: Off-white/Solid
• Density: 1.349 g/cm³
• Vapor Pressure: 0.0187mmHg at 25°C
• Refractive Index: 1.682
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 5-CHLOROBENZOTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLOROBENZOTHIOPHENE(20532-33-6)
• EPA Substance Registry System: 5-CHLOROBENZOTHIOPHENE(20532-33-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 20532-33-6(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

5-Chlorobenzo[b]thiophene is used as pharmaceutical intermediate.

InChI:InChI=1/C8H5ClS/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5H

Upstream product

• 110-81-6 Diethyl disulfide 
• 106-46-7 para-dichlorobenzene 

Downstream Products

• 13771-75-0 5-chloro-benzo(b)thiophene-2-carboxylic acid 
• 28540-36-5 5-chloro-3-phenylbenzo[b]thiophene 
• 101219-31-2 5-chloro-2-phenylbenzo[b]thiophene 
• 501945-71-7 2-(benzo[b]thiophen-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 35212-96-5 5-chloro-2-benzo[b]thiophenecarboxylic acid methyl ester 
• 125889-39-6 5-vinyl-2-nitropyridine 
• 99592-53-7 2-bromomethyl-5-chlorobenzo[b]thiophene 
• 13771-71-6 2-Hydroxymethyl-5-chlor-benzothiophen 

Relevant articles and documents

HIGH-TEMPERATURE ORGANIC SYNTHESIS. XVII. REACTION OF CHLOROBENZENE AND ITS DERIVATIVES WITH DIALKYL DISULFIDES

The products from the reaction of chlorobenzene with dialkyl disulfides in the gas phase at 550-650 deg C are benzene, thiophenol, diphenyl sulfide, and also toluene, thiophene, and benzothiophene.Diethyl disulfide is most reactive.Its copyrolysis with chlorobenzene is distinguished by high selectivity for the formation of thiophenol, the yield of which amounts to 60percent.In the reaction of substituted chlorobenzenes and also 2-chlorothiophene and 1-chloronaphthalene with diethyl disulfide the corresponding thiols were obtained with high yields.Two paths for the formation of thiophene during the pyrolysis of dialkyl disulfide were established, i.e., from vinyl hydrosulfide and S-butyl radical.The last reaction is realized at a high rate.