20532-34-7

Basic information

• Product Name: 1-BENZOTHIOPHEN-5-YLMETHANOL
• Synonyms: BUTTPARK 98\04-79;5-(HYDROXYMETHYL)BENZOTHIOPHENE;1-BENZOTHIOPHEN-5-YLMETHANOL;1-Benzothiophene-5-ylmethanol;1-Benzothien-5-ylmethanol;Benzo[b]thiophen-5-ylmethanol
• CAS NO: 20532-34-7
• Molecular Formula: C₉H₈OS
• Molecular Weight: 164.22
• Mol File: 20532-34-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 91 °C
• Boiling Point: 324 °C at 760 mmHg
• Flash Point: 149.8 °C
• Appearance: /
• Density: 1.294 g/cm³
• Vapor Pressure: 0.000103mmHg at 25°C
• Refractive Index: 1.698
• Storage Temp.: 2-8°C(protect from light)
• PKA: 14.30±0.10(Predicted)
• CAS DataBase Reference: 1-BENZOTHIOPHEN-5-YLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZOTHIOPHEN-5-YLMETHANOL(20532-34-7)
• EPA Substance Registry System: 1-BENZOTHIOPHEN-5-YLMETHANOL(20532-34-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 22-24/25-26
• Hazardous Substances Data: 20532-34-7(Hazardous Substances Data)

Usage

General Description

1-Benzothiophen-5-ylmethanol is a chemical compound with a molecular formula of C9H8OS. It is a white to off-white solid in appearance and is insoluble in water. 1-BENZOTHIOPHEN-5-YLMETHANOL is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and pigments. It is also a key intermediate in the manufacturing of various organic compounds and is known for its potential as a building block in the development of new chemical entities. Additionally, 1-Benzothiophen-5-ylmethanol has been studied for its potential biological and pharmacological properties, making it a versatile and valuable chemical in various industries.

InChI:InChI=1/C9H8OS/c10-6-7-1-2-9-8(5-7)3-4-11-9/h1-5,10H,6H2

Upstream product

• 2060-64-2 benzo[b]thiophene-5-carboxylic acid 
• 2060-63-1 benzo[b]thiophene-5-carbonitrile 
• 4923-87-9 5-bromobenzo[b]thiophene 
• 10133-22-9 5-bromomethyl-benzo[b]thiophene 

Relevant articles and documents

GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS

The present disclosure provides γ-diketones or analogs thereof, that activate Wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries or spine injuries, brain atrophy/neurological disorders related to the differentiation and development of the central nervous system, including Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; otic disorders like cochlear hair cell loss; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, such as hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

A novel preparation of 2-naphthyl and 5-benzo[B]thienyl methanesulfonyl chlorides

Electron rich arylmethylsulfonyl chlorides can be prepared from arylmethyl bromides by phase transfer sulfonation and chlorination with PCl5.