20532-34-7

Usage

Uses

Used in Pharmaceutical Industry:
1-Benzothiophen-5-ylmethanol is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological and pharmacological properties. It contributes to the development of new chemical entities with therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-Benzothiophen-5-ylmethanol is utilized as a building block in the production of agrochemicals, such as pesticides and herbicides, due to its chemical properties and reactivity.
Used in Dye and Pigment Production:
1-Benzothiophen-5-ylmethanol is employed in the manufacturing of dyes and pigments, where its chemical structure and properties contribute to the color and stability of these products.
Used in Organic Compound Synthesis:
As a versatile chemical intermediate, 1-Benzothiophen-5-ylmethanol is used in the synthesis of various organic compounds, enabling the creation of new molecules with diverse applications across different industries.

InChI:InChI=1/C9H8OS/c10-6-7-1-2-9-8(5-7)3-4-11-9/h1-5,10H,6H2

Upstream product

• 2060-64-2 benzo[b]thiophene-5-carboxylic acid 
• 2060-63-1 benzo[b]thiophene-5-carbonitrile 
• 4923-87-9 5-bromobenzo[b]thiophene 
• 10133-22-9 5-bromomethyl-benzo[b]thiophene 

Downstream Products

• 10133-30-9 benzo[b]thiophene-5-carbaldehyde 

Relevant academic research and scientific papers

GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS

The present disclosure provides γ-diketones or analogs thereof, that activate Wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries or spine injuries, brain atrophy/neurological disorders related to the differentiation and development of the central nervous system, including Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; otic disorders like cochlear hair cell loss; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, such as hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF

A benzophenone derivative represented by the following formula: whereinR1 represents, for example, an optionally substituted heterocyclic group, or a substituted phenyl group; Z represents, for example, an alkylene group; R2 represents, for example, a carboxyl group optionally protected with alkyl;R3 represents, for example, an optionally protected hydroxyl group; R4 represents, for example, an optionally substituted cycloalkyloxy group; and R5 represents, for example, a hydrogen atom, ???or a salt thereof has anti-arthritic activity, inhibits bone destruction caused by arthritis, and provides high safety and excellent pharmacokinetics and thus is useful as therapeutic agent for arthritis. These compounds have inhibitory effect on AP-1 activity and are useful as preventive or therapeutic agent for diseases in which excessive expression of AP-1 is involved.

A novel preparation of 2-naphthyl and 5-benzo[B]thienyl methanesulfonyl chlorides

Electron rich arylmethylsulfonyl chlorides can be prepared from arylmethyl bromides by phase transfer sulfonation and chlorination with PCl5.