205371-43-3

Usage

Structure

It is a benzaldehyde derivative with an ethoxy linker connecting to a 1H-imidazole group.

Application

Organic Synthesis: Used in organic chemistry for the creation of various compounds.
Pharmaceutical Research: Employed in the study of potential biological activities and drug development.

Biological Activity

Antifungal Properties: Reported to exhibit antifungal effects.
Antimicrobial Properties: Demonstrates antimicrobial activity.

Versatility

Chemical: Useful in various chemical reactions and syntheses.
Pharmaceutical: Potential applications in drug development and research.

Implications

Chemistry: Versatile compound for diverse chemical reactions.
Pharmaceuticals: Potential for the development of new drugs.
Biotechnology: Study of imidazole-containing compounds and their applications.

Potential Uses

Industrial Applications: Utilized in industrial processes.
Medical Applications: Potential for medical treatments due to its properties.

Overall Significance

Versatile compound with implications in chemistry, pharmaceuticals, and biotechnology.

InChI:InChI=1/C12H12N2O2/c15-9-11-1-3-12(4-2-11)16-8-7-14-6-5-13-10-14/h1-6,9-10H,7-8H2

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 288-32-4 1H-imidazole 
• 54373-15-8 4-(2-chloroethoxy)benzaldehyde 
• 52191-15-8 4-(2-bromoethyloxy)benzaldehyde 

Relevant academic research and scientific papers

Generation of catalytic amphiphiles in a self-reproducing giant vesicle

Giant vesicles capable of generating a catalytic amphiphile that promoted vesicular membrane production were prepared. The catalyst was derived from decylaniline on the vesicles and a catalytic aldehyde present outside the vesicles. Once the catalyst was

Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin

A series of novel monocarbonyl analogues of curcumin have been designed, synthesized and tested for their activity against Molt4, HeLa, PC3, DU145 and KB cancer cell lines. Six of the analogues showed potent cytotoxicity towards these cell lines with IC50 values below 1 μM, which is better than doxorubicin, a US FDA approved drug. Several analogues were also found to be active against both CQ-resistant (W2 clone) and CQ-sensitive (D6) strains of Plasmodium falciparum in an in-vitro antimalarial screening. This level of activity warrants further investigation of the compounds for development as anticancer and antimalarial agents.

SUBSTITUTED 1-AMINOPHTHALAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF

The invention concerns 1-amino-phthalazine derivatives of general formula (I): Wherein A, B, L, R, R1, R2, R3, R4, R5 and R7 are as defined herein. The invention also concerns the preparation of said compounds and their therapeutic use.

Novel euglycemic and hypolipidemic agents

A series of [[(heterocyclyl)ethoxy]benzyl]-2,4-thiazolidinediones have been synthesized by the condensation of corresponding aldehyde 1 and 2,4- thiazolidinedione followed by hydrogenation. Both unsaturated thiazolidinedione 2 and its saturated counterpar