205496-89-5Relevant academic research and scientific papers
A short asymmetric synthesis of (-)-neonepetalactone
Enders, Dieter,Kaiser, Anja
, p. 631 - 635 (1997)
(4S.,4aR)-Neonepetalactone (6) was synthesized in high diastereomeric and enantiomeric purity (de, ee ≥ 96 %) in a four step procedure. Key step of the total synthesis is the Michael addition of metalated propanal SAMP-hydrazone ((S)-1) to 2-cyclopentenecarboxylate (2).
