2055-26-7

Basic information

• Product Name: 2'-Methyl-6'-(3-pyridyl)-tetrahydro-1',2'-oxazin
• CAS NO: 2055-26-7
• Molecular Weight: 178.234
• Mol File: 2055-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-Methyl-6'-(3-pyridyl)-tetrahydro-1',2'-oxazin(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Methyl-6'-(3-pyridyl)-tetrahydro-1',2'-oxazin(2055-26-7)
• EPA Substance Registry System: 2'-Methyl-6'-(3-pyridyl)-tetrahydro-1',2'-oxazin(2055-26-7)

Safety Data

• Hazardous Substances Data: 2055-26-7(Hazardous Substances Data)

Upstream product

• 51095-86-4 trans-(S)-nicotine N-1'-oxide 
• 29419-54-3 nicotine-1'-N-oxide 

Downstream Products

• 16426-44-1 4-(methylamino)-1-(3'-pyridyl)-1-butanone dihydrochloride 
• 2055-27-8 (S)-4-methylamino-1-[3]pyridyl-butan-1-ol 

Relevant articles and documents

Determination of Nicotine N-Oxide by Gas Chromatography following Thermal Conversion to 2-Methyl-6-(3-pyridyl)tetrahydro-1,2-oxazine

Nicotine N-oxide is extracted from urine by use of silica gel columns and eluted with methanolic ammonia.The eluate is evaporated and then heated at 150-160 deg C in anisole, which results in conversion to the ring-expansion product 2-methyl-6-(3-pyridyl)tetrahydro-1,2-oxazine.The oxazine derivative is readily extracted from aqueous solution with organic solvents and has good chromatographic properties.A method for determination of nicotine N-oxide in smoker's urine, using 5-methylnicotine N-oxide as an internal standard, is described.