205643-06-7Relevant academic research and scientific papers
Design, synthesis and insight into the structure-activity relationship of 1,3-disubstituted indazoles as novel HIF-1 inhibitors
An, Hongchan,Kim, Nam-Jung,Jung, Jong-Wha,Jang, Hannah,Park, Jong-Wan,Suh, Young-Ger
, p. 6297 - 6300 (2011/11/29)
Design, synthesis and insight into the structure-activity relationship (SAR) of 1,3-disubstituted indazoles as novel HIF-1 inhibitors are described. In particular, the substituted furan moiety on indazole skeleton as well as its substitution pattern turns
ANTI-ANGIOGENESIS COMPOUNDS
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Page/Page column 127-128, (2010/11/27)
The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions
Blockade of voltage dependent sodium channels
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, (2008/06/13)
Compounds of formula (1), and pharmaceutically acceptable salts thereof, are capable of blockading voltage-dependent sodium channels and are useful in particular, in treating glaucoma and multiple sclerosis.
Heterocyclylmethyl-substituted pyrazole derivatives and their use for treating cardiovascular diseases
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, (2008/06/13)
PCT No. PCT/EP97/05432 Sec. 371 Date Apr. 9, 1999 Sec. 102(e) Date Apr. 9, 1999 PCT Filed Oct. 2, 1997 PCT Pub. No. WO98/16507 PCT Pub. Date Apr. 23, 1998The present invention relates to new heterocyclylmethyl-substituted pyrazole derivatives, processes f
