205643-28-3

Basic information

• Product Name: 1H-Indazole, 3-iodo-1-(phenylmethyl)-
• CAS NO: 205643-28-3
• Molecular Formula: C14H11IN2
• Molecular Weight: 334.159
• Mol File: 205643-28-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Indazole, 3-iodo-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole, 3-iodo-1-(phenylmethyl)-(205643-28-3)
• EPA Substance Registry System: 1H-Indazole, 3-iodo-1-(phenylmethyl)-(205643-28-3)

Safety Data

• Hazardous Substances Data: 205643-28-3(Hazardous Substances Data)

Usage

General Description

3-iodo-1-(phenylmethyl)-1H-indazole is a chemical compound with the molecular formula C15H12IN and a molecular weight of 359.17 g/mol. It is a substituted indazole derivative with a phenylmethyl group and an iodine atom attached to the third carbon in the indazole ring. 1H-Indazole, 3-iodo-1-(phenylmethyl)- is often used in medicinal and pharmaceutical research as a potential drug candidate, particularly in the development of new psychoactive and therapeutic agents. Its precise properties and potential uses are still under investigation and further study is needed to fully understand its pharmacological potential.

Upstream product

• 271-44-3 benzimidazole 
• 679794-95-7 3-trimethylsilylindazole 
• 741693-32-3 1-benzyl-3-trimethylsilylindazole 
• 66607-27-0 3-iodoindazole 
• 100-39-0 benzyl bromide 

Downstream Products

• 205643-02-3 1-Benzyl-3-[5-(1,3-dioxolan-2-yl)-furan-2-yl]-indazole 
• 849330-87-6 [5-(1-benzyl-1H-indazol-3-yl)-1-methyl-1H-pyrrol-2-yl]methanol 
• 849330-91-2 [5-(1-benzyl-1H-indazol-3-yl)-tetrahydro-furan-2-yl]methanol 
• 170632-42-5 1-benzyl-3-(5'-hydroxycarbonyl-2'-furyl)indazole 
• 205646-24-8 1-benzyl-1H-indazole-3-carbonitrile 
• 170632-13-0 1-benzyl-3-(5-methoxycarbonyl-furan-2-yl)-1H-indazole 
• 1345965-34-5 C₁₈H₁₅N₃O₂ 
• 205643-06-7 3-(5-Azidomethylfuran-2-yl)-1-benzyl-indazole 
• 1345965-42-5 C₂₄H₂₄N₂O₃ 
• 1345965-41-4 C₂₃H₂₂N₂O₃ 
• 205643-03-4 1-benzyl-3-(5-formyl-furan-2-yl)indazole 
• 130641-38-2 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid 
• 131427-22-0 1-benzyl-3-chloromethyl-1H-indazole 
• 131427-21-9 (1-Benzyl-1H-indazol-3-yl)-methanol 

Relevant articles and documents

Hypoxia-Targeting Organometallic Ru(II)-Arene Complexes with Enhanced Anticancer Activity in Hypoxic Cancer Cells

As hypoxia is an important factor to limit chemotherapeutic efficacy in tumors, we herein report three ruthenium(II)-arene complexes containing a hypoxia inducible factor-1α inhibitor (YC-1), which endow the organometallic complexes with potential for hyp

ANTI-ANGIOGENESIS COMPOUNDS

The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions

New synthesis of 3-substituted indazoles from 3-trimethylsilylindazole

Reaction of aryl aldehydes with 3-trimethylsilylindazole in the presence of CsF easily gave the corresponding 3-(arylhydroxymethyl)indazoles in good to moderate yields.