205643-09-0

Upstream product

• 271-44-3 benzimidazole 
• 205643-03-4 1-benzyl-3-(5-formyl-furan-2-yl)indazole 
• 232935-04-5 1-benzyl-3-(furan-2-yl)-1H-indazole 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 170632-47-0 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole 

Downstream Products

• 849330-91-2 [5-(1-benzyl-1H-indazol-3-yl)-tetrahydro-furan-2-yl]methanol 

Relevant academic research and scientific papers

ANTI-ANGIOGENESIS COMPOUNDS

The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions

COMPOUNDS, COMPOSITIONS AND METHODS

The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions.

Blockade of voltage dependent sodium channels

Compounds of formula (1), and pharmaceutically acceptable salts thereof, are capable of blockading voltage-dependent sodium channels and are useful in particular, in treating glaucoma and multiple sclerosis.