205647-74-1

Basic information

• Product Name: (R)-tert-butyl 2,2-dimethyl-4-[(tosyloxy)methyl]-oxazolidine-3-carboxylate
• Synonyms: (R)-tert-butyl 2,2-dimethyl-4-[(tosyloxy)methyl]-oxazolidine-3-carboxylate
• CAS NO: 205647-74-1
• Molecular Weight: 385.481
• Mol File: 205647-74-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 2,2-dimethyl-4-[(tosyloxy)methyl]-oxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 2,2-dimethyl-4-[(tosyloxy)methyl]-oxazolidine-3-carboxylate(205647-74-1)
• EPA Substance Registry System: (R)-tert-butyl 2,2-dimethyl-4-[(tosyloxy)methyl]-oxazolidine-3-carboxylate(205647-74-1)

Safety Data

• Hazardous Substances Data: 205647-74-1(Hazardous Substances Data)

Upstream product

• 108149-63-9 tert-butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 
• 98-59-9 p-toluenesulfonyl chloride 
• 95715-85-8 2-(tert-butoxycarbonylamino)-3-hydroxypropionic acid methyl ester 
• 108149-60-6 methyl [(4R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidin-4-yl]carboxylate 
• 108149-63-9 4-hydroxymethyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 1643461-35-1 (S)-tert-butyl 2,2-dimethyl-4-[(4-octylphenoxy)methyl]oxazolidine-3-carboxylate 
• 1643461-36-2 (R)-tert-butyl [1-hydroxy-3-(4-octylphenoxy)propan-2-yl]carbamate 
• 1643461-37-3 (S)-2-[(tert-butoxycarbonyl)amino]-3-(4-octylphenoxy)propyl 4-methylbenzenesulfonate 
• 1643461-44-2 (R)-allyl 1-{2-[(tert-butoxycarbonyl)amino]-3-(4-octylphenoxy)-propyl}indazole-5-carboxylate 
• 1643461-40-8 (S)-allyl 1-{2-[(tert-butoxycarbonyl)amino]-3-(tosyloxy)propyl}-indazole-5-carboxylate 
• 1643461-41-9 (S)-allyl 1-{2-[(tert-butoxycarbonyl)amino]-3-(4-octylphenoxy)-propyl}indazole-5-carboxylate 
• 1160984-88-2 (S)-4-(3-formyl-phenoxymethyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 205647-76-3 (S)-3-[4-Benzyloxy-3-((R)-2-tert-butoxycarbonylamino-3-hydroxy-propoxy)-phenyl]-2-(benzyloxycarbonyl-methyl-amino)-propionic acid methyl ester 
• 205647-75-2 (S)-4-{2-Benzyloxy-5-[(S)-2-(benzyloxycarbonyl-methyl-amino)-2-methoxycarbonyl-ethyl]-phenoxymethyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS

Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.

BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS

The present invention discloses bisphenyl compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, X, Y, W are defined herein after. These compounds are useful as pharmaceuticals.