205651-84-9Relevant academic research and scientific papers
Synthesis of chiral β-aminophosphonates via Rh-catalyzed asymmetric hydrogenation of β-amido-vinylphosphonates
Kadyrov, Renat,Holz, Jens,Schaeffner, Benjamin,Zayas, Odalys,Almena, Juan,Boerner, Armin
, p. 1189 - 1192 (2008)
The Rh-catalyzed asymmetric hydrogenation of prochiral β-N-acetylamino-vinylphosphonates allows the preparation of chiral β-N-acetylamino-phosphonates with excellent yields (up to 100%) and high enantioselectivities (up to 92% ee). The reaction is strongl
Asymmetric hydrogenation of α- And β-enamido phosphonates: Rhodium(I)/monodentate phosphoramidite catalyst
Zhang, Jinzhu,Li, Yang,Wang, Zheng,Ding, Kuiling
supporting information; scheme or table, p. 11743 - 11747 (2012/01/03)
High efficiency and enantioselectivity have been achieved in the Rh I-catalyzed asymmetric hydrogenation of α- and β-enamido phosphonates using a monophosphoramidite as the chiral ligand (see scheme; cod=1,5-cyclooctadiene), thus affording the optically active amino phosphonates with a turnover frequency of up to 1800 h-1 and high ee values. Copyright
