20568-98-3Relevant academic research and scientific papers
A Non-acid Methodology for Polynitration of Arenes at Low Temperatures
Suzuki, Hitomi,Murashima, Takashi,Shimizu, Kazuhiro,Tsukamoto, Kenkichi
, p. 1049 - 1050 (1991)
In the presence of ozone and an appropriate catalyst, nitrogen dioxide acts as a powerful nitrating agent at low temperatures, converting arenes into polynitro derivatives in good yields.
SUBSTITUTED NITROBENZENE DERIVATIVES AS MEDICINES AND OTHER USEFUL USES THEREOF
-
, (2008/06/13)
The present invention relates to a use of substituted nitrobenzene derivatives of general Formula I in medicine and health food, the pharmaceutical compositions comprising substituted nitrobenzene derivatives of general Formula I and the methods thereof for the prophylaxis and treatment of diseases.
Ozone-mediated Nitration of Alkylbenzenes and Related Compounds with Nitrogen Dioxide
Suzuki, Hitomi,Murashima, Takashi,Kozai, Iku,Mori, Tadashi
, p. 1591 - 1598 (2007/10/02)
In the presence of ozone, nitrogen dioxide exhibits a strong nitrating ability for alkylbenzenes at low temperatures, converting them into the corresponding nitro derivatives in high yield.The addition of a protonic acid as catalyst enhances considerably the ability of this nitrating system and leads to a good yield of polynitro compounds.The reaction is clean and proceeds rapidly without any accompanying side-chain substitution or aryl-aryl coupling.It shows no kinetic dependence on the concentration of substrates and, as far as can be judged from relative reactivities and isomer distributions of products, it gives the appearance of being an electrophilic aromatic process.A possible role for nitrogen trioxide has been suggested as the initial electrophilic agent for the nitration of alkylbenzenes.
A VERSATILE PREPARATION OF 2,6-DI-t-BUTYLBROMOBENZENE. APPLICATION TO STERIC PROTECTION FOR ORGANOPHOSPHORUS COMPOUNDS IN LOW COORDINATION STATES
Yoshifuji, Masaaki,Niitsu, Takashi,Shiomi, Daisuke,Inamoto, Naoki
, p. 5433 - 5436 (2007/10/02)
2,6-di-t-butylbromobenzene (5) was prepared from 2,4,6-tri-t-butyl-bromobenzene by ipso nitration followed by reduction of the nitro group and deamination.The diphosphene (8) and 1,3-diphosphaallene (10) were prepared.
