20570-20-1

Basic information

• Product Name: (Diethoxymethyl)diphenylphosphine oxide
• Synonyms: (Diethoxymethyl)diphenylphosphine oxide;Oxide
• CAS NO: 20570-20-1
• Molecular Formula: C₁₇H₂₁O₃P
• Molecular Weight: 304.32
• Mol File: 20570-20-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 73-75 °C
• Boiling Point: 381.2°C at 760 mmHg
• Flash Point: 197.9°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 1.13E-05mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: (Diethoxymethyl)diphenylphosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Diethoxymethyl)diphenylphosphine oxide(20570-20-1)
• EPA Substance Registry System: (Diethoxymethyl)diphenylphosphine oxide(20570-20-1)

Safety Data

• Hazardous Substances Data: 20570-20-1(Hazardous Substances Data)

Usage

General Description

(Diethoxymethyl)diphenylphosphine oxide is a chemical compound with the molecular formula C17H19O3P. It is a phosphine oxide derivative and consists of a diphenylphosphine group with two ethoxy methyl groups attached to the phosphorus atom. (Diethoxymethyl)diphenylphosphine oxide is commonly used as a ligand in organometallic chemistry and catalysis, due to its ability to coordinate with transition metals. It has been utilized in various organic synthesis reactions, including the formation of carbon-carbon and carbon-heteroatom bonds. (Diethoxymethyl)diphenylphosphine oxide is also known for its potential applications in the pharmaceutical and material science industries.

InChI:InChI=1/C17H21O3P/c1-3-19-17(20-4-2)21(18,15-11-7-5-8-12-15)16-13-9-6-10-14-16/h5-14,17H,3-4H2,1-2H3

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 1352709-73-9 (diphenylphosphoryl)(N,N-dimethylamino)chloromethane 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 86658-95-9 2-[(Diphenyl-phosphinoyl)-diethoxy-methyl]-adamantan-2-ol 
• 86658-97-1 (E)-1-(Diphenyl-phosphinoyl)-1,1-diethoxy-2-methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-but-3-en-2-ol 
• 188546-76-1 (R)-4-(tert-Butyl-diphenyl-silanyloxy)-1-(diphenyl-phosphinoyl)-1,1-diethoxy-pentan-2-ol 
• 188546-72-7 1,1-Diethoxy-2-hydroxy-2-naphthylethyldiphenylphosphine oxide 
• 86659-12-3 2-((E)-4,4-Diethoxy-3-methyl-buta-1,3-dienyl)-1,3,3-trimethyl-cyclohexene 
• 86659-01-0 (4,4-Diethoxy-but-3-enyl)-benzene 
• 86659-05-4 (2,2-Diethoxy-1-methyl-vinyl)-benzene 
• 86659-00-9 (2,2-Diethoxy-vinyl)-cyclohexane 
• 86659-08-7 Diethoxymethylene-cyclohexane 
• 188546-86-3 [4-(2,2-Diethoxy-vinyl)-phenyl]-dimethyl-amine 
• 13049-42-8 phenylketene diethylacetal 
• 1071215-45-6 tert-Butyl-((R)-4,4-diethoxy-1-methyl-but-3-enyloxy)-diphenyl-silane 
• 13049-42-8 C₁₂H₁₆O₂ 
• 86658-99-3 1-(2,2-Diethoxy-vinyl)-4-methoxy-benzene 

Relevant articles and documents

Ambident reactivity of chloro(dialkylamino)-(diphenylphosphinoyl)methanes

The chemical properties of chloro(dialkylamino)(diphenylphosphinoyl) methanes have been studied using the simplest compound of this series, chloro(dimethylamino)(diphenylphosphinoyl)methane, as an example. Chloro- (dimethylamino)(diphenylphosphinoyl)methane shows ambident reactivity when reacting with electrophiles and nucleophiles depending on coreactant nature, it behaves as either electrophilic substrate or phosphorus nucleophile. This fact can be explained by its dissociation in solutions with both C-Cl bond cleavage to give (dimethylamino)- (diphenylphosphinoyl)methyl cation and Cl- anion and C-P bond cleavage to form chloro(dimethylamino)methyl cation and diphenylphosphinite anion. The capability of chloro(dimethylamino) (diphenylphosphinoyl)methane to produce spontaneously Ph2PO-anion allows us to recommend application in organic and organophosphorus synthesis as a synthetic equivalent (synthon) of diphenylphosphinite anion.

12-hetero substituted 6,11-ethano-6,11-dihydrobenzo (b) quinolizinium salts and compositions and method of use thereof

1-Hetero substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.