205744-17-8

Basic information

• Product Name: 3-Pyridinemethanamine,6-fluoro-(9CI)
• Synonyms: (6-Fluoropyridin-3-yl);5-(Aminomethyl)-2-fluoropyridine;3-Pyridinemethanamine,6-fluoro-(9CI);2-fluoro-5-(aminomethyl)pyridine;6-Fluoro-3-pyridineMethanaMine
• CAS NO: 205744-17-8
• Molecular Formula: C₆H₇FN₂
• Molecular Weight: 126.13
• Product Categories: PYRIDINE
• Mol File: 205744-17-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 231.9 °C at 760 mmHg
• Flash Point: 94 °C
• Appearance: /
• Density: 1.18 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.73±0.29(Predicted)
• CAS DataBase Reference: 3-Pyridinemethanamine,6-fluoro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinemethanamine,6-fluoro-(9CI)(205744-17-8)
• EPA Substance Registry System: 3-Pyridinemethanamine,6-fluoro-(9CI)(205744-17-8)

Safety Data

• Hazardous Substances Data: 205744-17-8(Hazardous Substances Data)

Usage

Uses

6-Fluoro-3-pyridinemethanamine is a useful compound for the study of herbicidal activity of 2-cyano-3-[[(6-fluoro-3-pyridinyl)methyl]amino]acrylates.

Upstream product

• 3939-12-6 6-fluoro-3-pyridinecarbonitrile 
• 864061-60-9 N-(2-fluoro-5-pyridylmethyl)phthalimide 
• 105827-74-5 5-(Bromomethyl)-2-fluoropyridine 
• 2369-19-9 2-fluoro-5-methylpyridine 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 

Downstream Products

• 1135619-76-9 C₂₅H₂₀FN₃O₃ 
• 1135619-66-7 C₂₄H₁₈FN₃O₃ 
• 1135619-62-3 C₂₄H₁₈FN₃O₃ 

Relevant articles and documents

NAMPT/HDAC dual-target inhibitor and preparation method thereof

The invention discloses an NAMPT/HDAC dual-target inhibitor and a preparation method thereof. The dual-target inhibitor is an amide derivative and pharmaceutically acceptable salt thereof, wherein a structure general formula is represented as the formula

Synthesis and herbicidal activity of 2-cyano-3-(2-fluoro-5-pyridyl) methylaminoacrylates

A series of 2-cyano-3-(2-fluoro-5-pyridyl)methylaminoacrylates were synthesized as herbicidal inhibitors of photosystem II (PSII) electron transport. 2-Fluoro-5-pyridinemethylamine was prepared from 2-amino-5- methylpyridine, subsequent reaction with 2-cyano-3,3-dimethylthioacrylates or 2-cyano-3-methoxyacrylates to yield these title compounds. All of these compounds were confirmed by 1H NMR, IR, mass spectrum and elemental analyses. Their herbicidal activities were evaluated. All of the title compounds showed excellent herbicidal activities to amaranth pigweed and rape in post-emergence treatment. At the rate of 150 g/ha, one compound exhibited similar activity to Cl-analogue. The replacement of chlorine by fluorine group showed the same herbicidal activity.