220705-67-9 Usage
Uses
Used in Organic Synthesis:
1-Flormyl-1-(triisopropylsilyloxy)cyclopropane is used as a synthetic building block for the creation of more complex organic molecules. Its unique structure allows for a variety of chemical reactions, such as ring-opening, functional group transformations, and cross-coupling reactions, which can be employed to construct a wide range of target molecules with diverse applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Flormyl-1-(triisopropylsilyloxy)cyclopropane is used as a key intermediate in the synthesis of various drug candidates. Its reactivity and structural features enable the development of novel compounds with potential therapeutic properties, contributing to the discovery of new medicines for the treatment of various diseases.
Used in Material Science:
1-Flormyl-1-(triisopropylsilyloxy)cyclopropane is also utilized in the field of material science, where it serves as a precursor for the development of advanced materials with specific properties. These materials can be used in various applications, such as electronics, coatings, and adhesives, due to their unique characteristics derived from the cyclopropane-based structure.
Used in Chemical Research:
In academic and industrial research settings, 1-Flormyl-1-(triisopropylsilyloxy)cyclopropane is employed as a model compound for studying various aspects of organic chemistry, including reaction mechanisms, stereochemistry, and the development of new synthetic methods. Its unique structure and reactivity make it an ideal candidate for probing the fundamental principles of organic reactions and for testing new synthetic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 220705-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,7,0 and 5 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 220705-67:
(8*2)+(7*2)+(6*0)+(5*7)+(4*0)+(3*5)+(2*6)+(1*7)=99
99 % 10 = 9
So 220705-67-9 is a valid CAS Registry Number.
220705-67-9Relevant academic research and scientific papers
Experimental and Computational Studies on Rh(I)-Catalyzed Reaction of Siloxyvinylcyclopropanes and Diazoesters
Feng, Sheng,Wang, Kang,Ping, Yifan,Wang, Jianbo
supporting information, p. 21032 - 21039 (2020/12/21)
The Rh(I)-catalyzed reaction of siloxyvinylcyclopropanes and diazoesters leads to the formation of siloxyvinylcyclobutane and 1,4-diene derivatives. With [Rh(cod)Cl]2 as the catalyst, the formation of 1,4-diene was favored over the formation of siloxyvinylcyclobutane. By changing the catalyst to [Rh(cod)2OTf], siloxyvinylcyclobutane derivatives are formed with excellent chemoselectivities and in moderate to good yields. The alkene products are also obtained as single E configured isomers. A detailed mechanism for this transformation is proposed on the basis of mechanistic experiments and DFT calculations. The effect of catalysts on the chemoselectivity of these reactions is also examined computationally.
Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz
Markwalder, Jay A.,Christ, David D.,Mutlib, Abdul,Cordova, Beverly C.,Klabe, Ronald M.,Seitz, Steven P.
, p. 619 - 622 (2007/10/03)
Studies on the biotransformation of the clinically important non-nucleoside reverse transcriptase inhibitor efavirenz have shown that oxidation and secondary conjugation are important components of the processing of this molecule in vivo. We have synthesized metabolites of efavirenz to confirm their structure and to evaluate their activity as antivirals.
